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Articles Published Processes
10/16/2025 6:50:13 AM | Browse: 12 | Download: 23
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Received |
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2025-04-29 03:28 |
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Peer-Review Started |
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2025-05-08 09:11 |
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To Make the First Decision |
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Return for Revision |
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2025-05-22 11:36 |
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Revised |
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2025-06-03 14:20 |
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Second Decision |
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2025-09-11 02:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-11 07:49 |
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Articles in Press |
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2025-09-11 07:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-23 12:33 |
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Publish the Manuscript Online |
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2025-10-16 06:50 |
| ISSN |
1948-5190 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Evaluating the prognostic efficacy of biomarkers in pancreatic cyst fluid
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Orfeas P Varvarelis, Theodoros A Voulgaris, Androniki-Maria Skreka, Vasiliki Themelidi, Alexandra Voutsina and Antonios Vezakis |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Antonios Vezakis, Department of Endoscopy, 2ND Academic Surgical Unit, National and Kapodistrian University of Athens, Aretaieion Hospital, Athens 11528, Greece. avezakis@hotmail.com |
| Key Words |
Pancreatic cysts; Cyst fluid biomarkers; Endoscopic ultrasound; Prognostic evaluation; Moucinous cysts |
| Core Tip |
The analysis of pancreatic cyst fluid obtained via endoscopic ultrasound-guided fine-needle aspiration provides critical diagnostic and prognostic information. Conventional biomarkers, such as carcinoembryonic antigen and intra-cystic glucose, which can be offered as a point-of-care assay, remain valuable tools for distinguishing mucinous from non-mucinous cysts. However, neither reliably differentiates malignant from benign mucinous cysts. While emerging genetic markers represent a promising advancement, fine-needle biopsy remains the most reliable method for accurately characterizing cysts with malignant potential Continued progresses in molecular diagnostics and integrated clinical models are essential to optimize the management of pancreatic cystic lesions. |
| Publish Date |
2025-10-16 06:50 |
| Citation |
<p>Varvarelis OP, Voulgaris TA, Skreka AM, Themelidi V, Voutsina A, Vezakis A. Evaluating the prognostic efficacy of biomarkers in pancreatic cyst fluid. <i>World J Gastrointest Endosc</i> 2025; 17(10): 109037</p> |
| URL |
https://www.wjgnet.com/1948-5190/full/v17/i10/109037.htm |
| DOI |
https://dx.doi.org/10.4253/wjge.v17.i10.109037 |
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