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11/27/2025 7:53:58 AM | Browse: 2 | Download: 17
Publication Name World Journal of Hepatology
Manuscript ID 109051
Country China
Received
2025-04-29 05:55
Peer-Review Started
2025-05-07 09:18
First Decision by Editorial Office Director
2025-05-22 11:22
Return for Revision
2025-05-22 11:22
Revised
2025-06-05 09:20
Publication Fee Transferred
Second Decision by Editor
2025-10-11 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-11 13:02
Articles in Press
2025-10-11 13:02
Edit the Manuscript by Language Editor
2025-10-18 22:20
Typeset the Manuscript
2025-11-13 06:06
Publish the Manuscript Online
2025-11-27 07:53
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title PANoptosis in hepatocellular carcinoma: Underlying mechanisms
Manuscript Source Invited Manuscript
All Author List Meng-Jia Li, Chen-Lin Wen, Hai-Tao Cheng, Hao-Nan Lyu and Yang-Yang Han
ORCID
Author(s) ORCID Number
Yang-Yang Han http://orcid.org/0009-0005-9284-5530
Funding Agency and Grant Number
Funding Agency Grant Number
Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases No. XJDFB2024G02
National Natural Science Foundation of China No. 82260493
Corresponding Author Yang-Yang Han, Associate Professor, PhD, Department of Biology, School of Basic Medical Sciences, Xinjiang Medical University, No. 567 Shangde North Road, Urumqi 830017, Xinjiang Uygur Autonomous Region, China. yyhan@xjmu.edu.cn
Key Words Treatment strategies; Mechanisms; Programmed cell death; Hepatocellular carcinoma; PANoptosis
Core Tip This article interprets the specific mechanisms of PANoptosis in hepatocellular carcinoma (HCC) and explores potential therapeutic strategies, highlighting the promise of targeting PANoptosis for HCC treatment. While modulating PANoptosis in liver cancer cells can influence tumor progression, excessive activation of PANoptosis may trigger an inflammatory storm. We summarize current research on the mechanisms and therapies related to PANoptosis in HCC, aiming to provide possible treatment strategies for the disease.
Publish Date 2025-11-27 07:53
Citation

Li MJ, Wen CL, Cheng HT, Lyu HN, Han YY. PANoptosis in hepatocellular carcinoma: Underlying mechanisms. World J Hepatol 2025; 17(11): 109051

URL https://www.wjgnet.com/1948-5182/full/v17/i11/109051.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i11.109051
Full Article (PDF) WJH-17-109051-with-cover.pdf
Manuscript File 109051_Auto_Edited_111243.docx
Answering Reviewers 109051-answering-reviewers.pdf
Audio Core Tip 109051-audio.mp3
Conflict-of-Interest Disclosure Form 109051-conflict-of-interest-statement.pdf
Copyright License Agreement 109051-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 109051-non-native-speakers.pdf
Peer-review Report 109051-peer-reviews.pdf
Scientific Misconduct Check 109051-scientific-misconduct-check.png
Scientific Editor Work List 109051-scientific-editor-work-list.pdf
CrossCheck Report 109051-crosscheck-report.pdf