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Articles Published Processes
9/23/2025 6:49:00 AM | Browse: 44 | Download: 15
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Received |
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2025-04-30 07:50 |
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Peer-Review Started |
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2025-04-30 07:50 |
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To Make the First Decision |
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Return for Revision |
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2025-05-17 07:39 |
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Revised |
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2025-05-28 22:12 |
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Second Decision |
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2025-08-20 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-20 11:04 |
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Articles in Press |
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2025-08-20 11:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-11 01:00 |
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Publish the Manuscript Online |
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2025-09-23 06:49 |
ISSN |
2218-4333 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cell Biology |
Manuscript Type |
Review |
Article Title |
Prospects and challenges of novel natural marine-derived compounds in melanoma treatment
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Manuscript Source |
Invited Manuscript |
All Author List |
Kai Zheng, Yuan Zhou, Te Ba and Zi-Wei Yang |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Zi-Wei Yang, PhD, Department of Burn Surgery, The Third Affiliated Hospital of Inner Mongolia Medical University (Inner Mongolia Bao Gang Hospital), No. 20 Shaoxian Road, Kundulun District, Baotou 014000, Inner Mongolia Autonomous Region, China. ziweiyang1991@163.com |
Key Words |
Melanoma; Natural marine-derived compounds; Therapeutic applications; Traditional therapies; Clinical translation |
Core Tip |
Marine populations represent reservoirs of novel bioactive metabolites with diverse groups of chemical structures. Marine–derived compounds offer promising therapeutic avenues for melanoma by targeting multiple pathways involved in tumor growth, metastasis, and immune regulation. This review delineates the antitumor mechanisms of these therapies and evaluates their efficacy and safety in comparison to traditional treatment modalities. It also highlights emerging strategies for clinical translation, particularly the integration of patient–derived organoid models for preclinical validation. Leveraging these advanced models may bridge the gap between in vitro research and clinical application, facilitating the development of personalized, multimodal melanoma therapies. |
Publish Date |
2025-09-23 06:49 |
Citation |
<p>Zheng K, Zhou Y, Ba T, Yang ZW. Prospects and challenges of novel natural marine-derived compounds in melanoma treatment. <i>World J Clin Oncol</i> 2025; 16(9): 109079</p> |
URL |
https://www.wjgnet.com/2218-4333/full/v16/i9/109079.htm |
DOI |
https://dx.doi.org/10.5306/wjco.v16.i9.109079 |
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