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9/23/2025 6:49:00 AM | Browse: 44 | Download: 15
Publication Name World Journal of Clinical Oncology
Manuscript ID 109079
Country China
Received
2025-04-30 07:50
Peer-Review Started
2025-04-30 07:50
To Make the First Decision
Return for Revision
2025-05-17 07:39
Revised
2025-05-28 22:12
Second Decision
2025-08-20 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-20 11:04
Articles in Press
2025-08-20 11:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-11 01:00
Publish the Manuscript Online
2025-09-23 06:49
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Prospects and challenges of novel natural marine-derived compounds in melanoma treatment
Manuscript Source Invited Manuscript
All Author List Kai Zheng, Yuan Zhou, Te Ba and Zi-Wei Yang
ORCID
Author(s) ORCID Number
Kai Zheng http://orcid.org/0009-0009-6630-3200
Zi-Wei Yang http://orcid.org/0000-0003-1409-9841
Funding Agency and Grant Number
Corresponding Author Zi-Wei Yang, PhD, Department of Burn Surgery, The Third Affiliated Hospital of Inner Mongolia Medical University (Inner Mongolia Bao Gang Hospital), No. 20 Shaoxian Road, Kundulun District, Baotou 014000, Inner Mongolia Autonomous Region, China. ziweiyang1991@163.com
Key Words Melanoma; Natural marine-derived compounds; Therapeutic applications; Traditional therapies; Clinical translation
Core Tip Marine populations represent reservoirs of novel bioactive metabolites with diverse groups of chemical structures. Marine–derived compounds offer promising therapeutic avenues for melanoma by targeting multiple pathways involved in tumor growth, metastasis, and immune regulation. This review delineates the antitumor mechanisms of these therapies and evaluates their efficacy and safety in comparison to traditional treatment modalities. It also highlights emerging strategies for clinical translation, particularly the integration of patient–derived organoid models for preclinical validation. Leveraging these advanced models may bridge the gap between in vitro research and clinical application, facilitating the development of personalized, multimodal melanoma therapies.
Publish Date 2025-09-23 06:49
Citation <p>Zheng K, Zhou Y, Ba T, Yang ZW. Prospects and challenges of novel natural marine-derived compounds in melanoma treatment. <i>World J Clin Oncol</i> 2025; 16(9): 109079</p>
URL https://www.wjgnet.com/2218-4333/full/v16/i9/109079.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i9.109079
Full Article (PDF) WJCO-16-109079-with-cover.pdf
Manuscript File 109079_Auto_Edited_030847.docx
Answering Reviewers 109079-answering-reviewers.pdf
Audio Core Tip 109079-audio.mp3
Conflict-of-Interest Disclosure Form 109079-conflict-of-interest-statement.pdf
Copyright License Agreement 109079-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 109079-non-native-speakers.pdf
Peer-review Report 109079-peer-reviews.pdf
Scientific Misconduct Check 109079-scientific-misconduct-check.png
Scientific Editor Work List 109079-scientific-editor-work-list.pdf
CrossCheck Report 109079-crosscheck-report.pdf