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10/16/2025 9:32:18 AM | Browse: 12 | Download: 51
Publication Name World Journal of Orthopedics
Manuscript ID 109095
Country Russia
Received
2025-04-30 05:59
Peer-Review Started
2025-04-30 06:00
To Make the First Decision
Return for Revision
2025-05-23 11:35
Revised
2025-06-04 20:12
Second Decision
2025-09-01 02:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-01 09:05
Articles in Press
2025-09-01 09:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-23 00:37
Publish the Manuscript Online
2025-10-16 09:32
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Systematic Reviews
Article Title Spinal involvement in chronic recurrent multifocal osteomyelitis - diagnostics, treatment and what remains in the shadows: A literature review
Manuscript Source Invited Manuscript
All Author List Veronika V Petukhova, Alexey S Maletin, Alexander Yu Mushkin and Mikhail M Kostik
ORCID
Author(s) ORCID Number
Veronika V Petukhova http://orcid.org/0000-0002-2358-5529
Alexey S Maletin http://orcid.org/0000-0002-9250-8850
Alexander Yu Mushkin http://orcid.org/0000-0002-1342-3278
Mikhail M Kostik http://orcid.org/0000-0002-1180-8086
Funding Agency and Grant Number
Corresponding Author Mikhail M Kostik, MD, PhD, Professor, Hospital Pediatry, Saint-Petersburg State Pediatric Medical University, Lytovskaya 2, Saint Petersburg 194100, Russia. kost-mikhail@yandex.ru
Key Words Chronic recurrent multifocal osteomyelitis; Nonbacterial osteomyelitis; Whole-body magnetic resonance imaging; Nonsteroid anti-inflammatory drugs; Bisphosphonates; Tumor necrosis factor-alpha inhibitors
Core Tip Non-bacterial osteomyelitis with vertebrae involvement has differences not only in clinical and laboratory features but also in the effectiveness of therapeutic options. The literature on this issue is extremely scarce, mainly focusing on the diagnostic and imaging features of the disease. The analysis of 63 publications (2005-2024) selected by the keywords "chronic recurrent multifocal osteomyelitis", "spine", "vertebral form of non-bacterial osteomyelitis", and "SAPHO" is presented. The researchers' consensus emphasizes the variety of radiation manifestations, the need to integrate whole-body magnetic resonance imaging into the diagnostic algorithm, the possibility of spinal complications (including spinal deformities and neurological complications), and the step-by-step principle of treatment, with a recommendation to include bisphosphonates in the first line of therapy.
Publish Date 2025-10-16 09:32
Citation <p>Petukhova VV, Maletin AS, Mushkin AY, Kostik MM. Spinal involvement in chronic recurrent multifocal osteomyelitis - diagnostics, treatment and what remains in the shadows: A literature review. <i>World J Orthop</i> 2025; 16(10): 109095</p>
URL https://www.wjgnet.com/2218-5836/full/v16/i10/109095.htm
DOI https://dx.doi.org/10.5312/wjo.v16.i10.109095
Full Article (PDF) WJO-16-109095-with-cover.pdf
PRISMA 2009 Checklist 109095-PRISMA-2009-Checklist.pdf
Manuscript File 109095_Auto_Edited_033130.docx
Answering Reviewers 109095-answering-reviewers.pdf
Audio Core Tip 109095-audio.m4a
Biostatistics Review Certificate 109095-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 109095-conflict-of-interest-statement.pdf
Copyright License Agreement 109095-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 109095-non-native-speakers.pdf
Peer-review Report 109095-peer-reviews.pdf
Scientific Misconduct Check 109095-scientific-misconduct-check.png
Scientific Editor Work List 109095-scientific-editor-work-list.pdf
CrossCheck Report 109095-crosscheck-report.pdf