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Articles Published Processes
8/21/2025 5:29:11 AM | Browse: 78 | Download: 272
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Received |
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2025-04-30 07:56 |
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Peer-Review Started |
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2025-04-30 07:57 |
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First Decision by Editorial Office Director |
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2025-05-27 08:42 |
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Return for Revision |
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2025-05-27 08:42 |
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Revised |
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2025-06-10 05:38 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-07-14 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-14 09:58 |
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Articles in Press |
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2025-07-14 09:58 |
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Edit the Manuscript by Language Editor |
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2025-07-17 21:11 |
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Typeset the Manuscript |
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2025-08-11 07:38 |
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Publish the Manuscript Online |
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2025-08-21 05:29 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Advancing mechanistic insights and clinical translation of exosomal miR-137-3p in endometrial regeneration
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lin-Fen Han, Guo-Kai Fu, Yue-Qi Wen and Xue-Li Bian |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xue-Li Bian, Full Professor, PhD, School of Basic Medical Science, Nanchang University, No. 1299 Xuefu Road, Honggutan District, Nanchang 330031, Jiangxi Province, China. bianxueli@ncu.edu.cn |
| Key Words |
Exosomal miR-137-3p; Ubiquitin protein ligase E3C; Signal transducer and activator of transcription 3; Human umbilical cord mesenchymal stem cells; Endometrial regeneration; Clinical translation |
| Core Tip |
Zhang et al employed integrated bioinformatics analysis and functional validation to demonstrate that hypoxia-induced exosomal miR-137-3p promotes human umbilical cord mesenchymal stem cell migration and differentiation into endometrial epithelial cells by targeting ubiquitin protein ligase E3C and activating the signal transducer and activator of transcription 3. These findings provide novel insights into exosome-mediated stem cell therapy for thin endometrium. This article underscores the paramount importance of elucidating underlying mechanisms and rigorously assessing translational potential. Further investigation focusing on mechanism depth and transformation feasibility is essential to robustly facilitate the clinical translation of this promising therapeutic strategy. |
| Publish Date |
2025-08-21 05:29 |
| Citation |
Han LF, Fu GK, Wen YQ, Bian XL. Advancing mechanistic insights and clinical translation of exosomal miR-137-3p in endometrial regeneration. World J Stem Cells 2025; 17(8): 109106 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i8/109106.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i8.109106 |
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