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12/19/2025 8:32:40 AM | Browse: 21 | Download: 131
Publication Name World Journal of Experimental Medicine
Manuscript ID 109134
Country India
Received
2025-04-30 03:42
Peer-Review Started
2025-05-06 09:23
First Decision by Editorial Office Director
2025-05-17 15:04
Return for Revision
2025-05-17 15:04
Revised
2025-06-09 13:27
Publication Fee Transferred
Second Decision by Editor
2025-10-14 02:49
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-15 07:12
Articles in Press
2025-10-15 07:12
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-28 09:33
Publish the Manuscript Online
2025-12-19 08:32
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Prospective Study
Article Title Stepwise model to differentiate pathogenic from non-pathogenic organisms in urinary isolates: Effectiveness, safety, and feasibility prospective study
Manuscript Source Invited Manuscript
All Author List Bimalesh Yadav, Jaideep Pilania, Ravi Kant, Balram Ji Omar, Sandeep Saini, Vikas Kumar Panwar, Yogesh Bahurupi and Prasan Kumar Panda
ORCID
Author(s) ORCID Number
Ravi Kant http://orcid.org/0000-0003-1144-4478
Prasan Kumar Panda http://orcid.org/0000-0002-3008-7245
Funding Agency and Grant Number
Corresponding Author Prasan Kumar Panda, Professor, Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Department of Medicine, All India Institute of Medical Sciences, Rishikesh, Room No. 409, Department of Medicine, College Block, Rishikesh 249203, India. motherprasanna@rediffmail.com
Key Words Colonization; Contamination; Clinical decision-making; Feasibility studies; Inappropriate prescribing
Core Tip Differentiating true pathogens from colonizers or contaminants in urinary cultures remains a major challenge in clinical practice. This study presents a novel, stepwise model to assess the true pathogenicity of urinary isolates in hospitalized adults. The model identified nearly 10% of culture-positive cases—previously treated as infections—as non-pathogenic. This approach is safe, feasible, and potentially reduces unnecessary antibiotic use, especially in resource-limited settings.
Publish Date 2025-12-19 08:32
Citation

Yadav B, Pilania J, Kant R, Omar BJ, Saini S, Panwar VK, Bahurupi Y, Panda PK. Stepwise model to differentiate pathogenic from non-pathogenic organisms in urinary isolates: Effectiveness, safety, and feasibility prospective study. World J Exp Med 2025; 15(4): 109134

URL https://www.wjgnet.com/2220-315x/full/v15/i4/109134.htm
DOI https://dx.doi.org/10.5493/wjem.v15.i4.109134
Full Article (PDF) WJEM-15-109134-with-cover.pdf
CONSORT 2010 Statement 109134-CONSORT-2010-statement.pdf
Manuscript File 109134_Auto_Edited_081240.docx
Answering Reviewers 109134-answering-reviewers.pdf
Audio Core Tip 109134-audio.mp3
Biostatistics Review Certificate 109134-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 109134-conflict-of-interest-statement.pdf
Copyright License Agreement 109134-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 109134-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 109134-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 109134-non-native-speakers.pdf
Peer-review Report 109134-peer-reviews.pdf
Scientific Misconduct Check 109134-scientific-misconduct-check.png
Scientific Editor Work List 109134-scientific-editor-work-list.pdf
CrossCheck Report 109134-crosscheck-report.pdf