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Articles Published Processes
8/8/2025 9:09:11 AM | Browse: 107 | Download: 397
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Received |
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2025-05-06 09:46 |
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Peer-Review Started |
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2025-05-06 09:46 |
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First Decision by Editorial Office Director |
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2025-06-10 07:14 |
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Return for Revision |
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2025-06-10 07:14 |
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Revised |
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2025-06-13 02:26 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-07-10 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-10 07:46 |
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Articles in Press |
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2025-07-10 07:46 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-01 03:45 |
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Publish the Manuscript Online |
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2025-08-08 09:09 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Editorial |
| Article Title |
Advancing bone regeneration: Clinical implications of synthetic biomaterials and fibrin derivatives
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ren-Xian Xie, Yi-Xuan Xing and Nian-Zhe Sun |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Nian-Zhe Sun, MD, Department of Orthopedics, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 410008, Hunan Province, China. sunnzh201921@sina.com |
| Key Words |
Biomaterials; Bone regeneration; Fibrin sealant; Hydroxyapatite; Regenerative medicine |
| Core Tip |
The integration of synthetic biomaterials, for example hydroxyapatite and β-tricalcium phosphate, with fibrin derivatives enhances bone regeneration by improving scaffold stability, cellular recruitment, and mechanical support. While promising, clinical adoption requires standardized protocols, long-term outcome validation, and personalized approaches to address complex bone defects in aging and comorbid populations. |
| Publish Date |
2025-08-08 09:09 |
| Citation |
Xie RX, Xing YX, Sun NZ. Advancing bone regeneration: Clinical implications of synthetic biomaterials and fibrin derivatives. World J Orthop 2025; 16(8): 109149 |
| URL |
https://www.wjgnet.com/2218-5836/full/v16/i8/109149.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v16.i8.109149 |
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