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9/25/2025 9:22:04 AM | Browse: 65 | Download: 27
Publication Name World Journal of Virology
Manuscript ID 109170
Country India
Received
2025-05-06 03:59
Peer-Review Started
2025-05-06 04:02
To Make the First Decision
Return for Revision
2025-05-17 15:26
Revised
2025-05-28 18:08
Second Decision
2025-09-01 02:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-01 08:53
Articles in Press
2025-09-01 08:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-11 01:58
Publish the Manuscript Online
2025-09-25 09:22
ISSN 2220-3249 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Virology
Manuscript Type Retrospective Study
Article Title Pre-hospital proton pump inhibitor use and clinical outcomes in hospitalized COVID-19 patients: A retrospective case-control study
Manuscript Source Invited Manuscript
All Author List Harinivaas Shanmugavel Geetha, Sushmita Prabhu, Mithil Gowda Suresh, George M Abraham, Akshaya Sekar, Safia Mohamed, Abinesh Sekar, Juniali Hatwal, Aalam Sohal and Akash Batta
ORCID
Author(s) ORCID Number
Harinivaas Shanmugavel Geetha http://orcid.org/0000-0001-6293-208X
Sushmita Prabhu http://orcid.org/0000-0002-6186-8132
Mithil Gowda Suresh http://orcid.org/0000-0002-1495-5444
George M Abraham http://orcid.org/0000-0003-4296-8362
Juniali Hatwal http://orcid.org/0000-0001-5433-0433
Aalam Sohal http://orcid.org/0000-0001-8365-7240
Akash Batta http://orcid.org/0000-0002-7606-5826
Funding Agency and Grant Number
Corresponding Author Akash Batta, Associate Professor, Department of Cardiology, Dayanand Medical College and Hospital, Tagore Nagar, Civil Lines, Ludhiana 141001, Punjab, India. akashbatta02@gmail.com
Key Words Comorbidities; Case-control study; mortality; Intensive care unit; Proton pump inhibitors; SARS-CoV-2; COVID-19
Core Tip This retrospective case-control study investigated the association between pre-hospital proton pump inhibitor (PPI) use and outcomes among patients hospitalized with coronavirus disease 2019 (COVID-19). After adjusting for multiple confounders, pre-hospital PPI use was associated with a lower risk of intensive care unit admission and in-hospital mortality. While the underlying mechanisms remain unclear, the findings suggest that chronic PPI use may not be associated with adverse COVID-19 outcomes.
Publish Date 2025-09-25 09:22
Citation <p>Shanmugavel Geetha H, Prabhu S, Suresh MG, Abraham GM, Sekar A, Mohamed S, Sekar A, Hatwal J, Sohal A, Batta A. Pre-hospital proton pump inhibitor use and clinical outcomes in hospitalized COVID-19 patients: A retrospective case-control study. <i>World J Virol</i> 2025; 14(3): 109170</p>
URL https://www.wjgnet.com/2220-3249/full/v14/i3/109170.htm
DOI https://dx.doi.org/10.5501/wjv.v14.i3.109170
Full Article (PDF) WJV-14-109170-with-cover.pdf
Manuscript File 109170_Auto_Edited_091245.docx
Answering Reviewers 109170-answering-reviewers.pdf
Audio Core Tip 109170-audio.m4a
Biostatistics Review Certificate 109170-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 109170-conflict-of-interest-statement.pdf
Copyright License Agreement 109170-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 109170-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 109170-institutional-review-board-statement.pdf
Peer-review Report 109170-peer-reviews.pdf
Scientific Misconduct Check 109170-scientific-misconduct-check.png
Scientific Editor Work List 109170-scientific-editor-work-list.pdf
CrossCheck Report 109170-crosscheck-report.pdf