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9/25/2025 11:24:05 AM | Browse: 65 | Download: 72
Publication Name World Journal of Hepatology
Manuscript ID 109179
Country Viet Nam
Received
2025-05-08 09:08
Peer-Review Started
2025-05-12 00:10
To Make the First Decision
Return for Revision
2025-06-05 09:30
Revised
2025-06-28 14:52
Second Decision
2025-08-21 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-21 03:21
Articles in Press
2025-08-21 03:21
Publication Fee Transferred
2025-07-18 10:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-17 03:13
Publish the Manuscript Online
2025-09-25 11:24
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Evaluating thresholds of Mac-2 binding protein glycosylation isomer in association with clinical outcomes in patients with cirrhosis
Manuscript Source Unsolicited Manuscript
All Author List Trung Hieu Doan, Khue Minh Nguyen, Xung Van Nguyen, Anh Thi Ngoc Pham and Nhan Duc Le
ORCID
Author(s) ORCID Number
Khue Minh Nguyen http://orcid.org/0009-0006-0992-4092
Funding Agency and Grant Number
Corresponding Author Nhan Duc Le, Intensive Care Unit, Danang Hospital, Danang 50000, Viet Nam. drnhandanang@gmail.com
Key Words Cirrhosis; Hepatocellular carcinoma; Esophageal varices; High-risk esophageal varices; Liver decompensation; Mac-2 binding protein glycosylation isomer
Core Tip This study introduces serum mac-2 binding protein glycosylation isomer (M2BPGi) as a novel biomarker for predicting complications in cirrhotic patients, particularly hepatocellular carcinoma (HCC), liver decompensation, and esophageal varices. The findings show that combining M2BPGi with alpha-fetoprotein significantly enhances diagnostic accuracy, achieving an impressive sensitivity of 92.8% for HCC detection. Importantly, M2BPGi levels correlate with disease severity as measured by the Child-Pugh classification, highlighting its potential role in clinical risk stratification.
Publish Date 2025-09-25 11:24
Citation <p>Doan TH, Nguyen KM, Nguyen XV, Pham ATN, Le ND. Evaluating thresholds of Mac-2 binding protein glycosylation isomer in association with clinical outcomes in patients with cirrhosis. <i>World J Hepatol</i> 2025; 17(9): 109179</p>
URL https://www.wjgnet.com/1948-5182/full/v17/i9/109179.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i9.109179
Full Article (PDF) WJH-17-109179-with-cover.pdf
CONSORT 2010 Statement 109179-CONSORT-2010-statement.pdf
Manuscript File 109179_Auto_Edited_033654.docx
Answering Reviewers 109179-answering-reviewers.pdf
Audio Core Tip 109179-audio.m4a
Biostatistics Review Certificate 109179-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 109179-conflict-of-interest-statement.pdf
Copyright License Agreement 109179-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 109179-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 109179-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 109179-non-native-speakers.pdf
Peer-review Report 109179-peer-reviews.pdf
Scientific Misconduct Check 109179-scientific-misconduct-check.png
Scientific Editor Work List 109179-scientific-editor-work-list.pdf
CrossCheck Report 109179-crosscheck-report.pdf