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Articles Published Processes
10/25/2025 1:11:34 AM | Browse: 200 | Download: 430
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Received |
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2025-05-08 05:52 |
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Peer-Review Started |
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2025-05-08 05:52 |
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First Decision by Editorial Office Director |
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2025-06-12 07:07 |
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Return for Revision |
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2025-06-12 07:07 |
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Revised |
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2025-06-24 08:26 |
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Publication Fee Transferred |
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2025-06-25 01:10 |
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Second Decision by Editor |
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2025-08-26 08:33 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-27 10:03 |
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Articles in Press |
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2025-08-27 10:03 |
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Edit the Manuscript by Language Editor |
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2025-09-02 19:11 |
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Typeset the Manuscript |
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2025-10-15 07:32 |
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Publish the Manuscript Online |
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2025-10-25 01:11 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Melanoma cell adhesion molecule-positive mesenchymal stromal cells alleviate acute respiratory distress syndrome via nuclear factor kappa-B-mediated paracrine regulation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ya-Li Zhang, Ding-Ke Wen, Sheng-Nan Wang, Yi Tan and He-Ran Ma |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology SMEs Innovation Capacity Improvement Project of Shandong Province |
2022TSGC1004 |
| National Key R&D Program of China |
2021YFA1101502 |
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| Corresponding Author |
He-Ran Ma, Manager, PhD, Department of Research and Development, Qilu Cell Therapy Technology Co., Ltd, No. 6 Gangyuan Road, Licheng District, Jinan 250000, Shandong Province, China. maheran@yinfeng.com.cn |
| Key Words |
Mesenchymal stromal cells; Melanoma cell adhesion molecule; Acute respiratory distress syndrome; Nuclear factor kappa B; CD146 |
| Core Tip |
Mesenchymal stromal cells (MSCs) are recognized for their immunosuppressive properties and are widely used to control excessive inflammation. This study demonstrated that, compared with CD146- MSCs, CD146+ MSCs exhibit greater secretion of pro-angiogenic factors and enhanced anti-inflammatory and immunomodulatory capacities. CD146+ MSCs repair epithelial cells by activating the nuclear factor kappa B/cyclooxygenase 2 pathway, thereby exerting superior therapeutic efficacy in the treatment of acute respiratory distress syndrome. |
| Publish Date |
2025-10-25 01:11 |
| Citation |
Zhang YL, Wen DK, Wang SN, Tan Y, Ma HR. Melanoma cell adhesion molecule-positive mesenchymal stromal cells alleviate acute respiratory distress syndrome via nuclear factor kappa-B-mediated paracrine regulation. World J Stem Cells 2025; 17(10): 109284 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i10/109284.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i10.109284 |
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