BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/25/2025 11:24:05 AM | Browse: 64 | Download: 26
Publication Name World Journal of Hepatology
Manuscript ID 109340
Country China
Received
2025-05-08 09:06
Peer-Review Started
2025-05-19 00:43
To Make the First Decision
Return for Revision
2025-06-07 05:54
Revised
2025-06-21 02:11
Second Decision
2025-09-01 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-02 00:58
Articles in Press
2025-09-02 00:58
Publication Fee Transferred
2025-07-08 15:28
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-17 03:14
Publish the Manuscript Online
2025-09-25 11:24
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Functional cure in an occult hepatitis B virus infection patient on sequential therapy: A case report
Manuscript Source Unsolicited Manuscript
All Author List Lin Wang, Han Liang, Chen Wang, Meng-Yu Liang, Qing-Lei Zeng, Peng-Fei Zhu and Jun Lv
ORCID
Author(s) ORCID Number
Lin Wang http://orcid.org/0009-0003-6451-9733
Peng-Fei Zhu http://orcid.org/0000-0002-6542-6673
Jun Lv http://orcid.org/0000-0002-9931-0505
Funding Agency and Grant Number
Corresponding Author Jun Lv, Associate Chief Physician, Associate Professor, Department of Infectious Diseases, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou 450052, Henan Province, China. fcclvj@zzu.edu.cn
Key Words Chronic hepatitis B; Occult hepatitis B virus infection; Sequential combined therapy; Functional cure; Case report
Core Tip This case illustrates the emergence of occult hepatitis B infection (OBI) as a distinct transitional phase during sequential combination therapy for chronic hepatitis B. Unlike previously reported cases where OBI develops in individuals with resolved infection, this case suggests that antiviral therapy itself may induce an OBI-like state before achieving functional cure. As OBI has been associated with potential reactivation risks. Understanding the mechanisms behind treatment-induced OBI will be crucial in refining therapeutic strategies and improving long-term hepatitis B virus management.
Publish Date 2025-09-25 11:24
Citation <p>Wang L, Liang H, Wang C, Liang MY, Zeng QL, Zhu PF, Lv J. Functional cure in an occult hepatitis B virus infection patient on sequential therapy: A case report. <i>World J Hepatol</i> 2025; 17(9): 109340</p>
URL https://www.wjgnet.com/1948-5182/full/v17/i9/109340.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i9.109340
Full Article (PDF) WJH-17-109340-with-cover.pdf
CARE Checklist–2016 109340-CARE-Checklist-2016.pdf
Manuscript File 109340_Auto_Edited_095021.docx
Answering Reviewers 109340-answering-reviewers.pdf
Audio Core Tip 109340-audio.mp3
Conflict-of-Interest Disclosure Form 109340-conflict-of-interest-statement.pdf
Copyright License Agreement 109340-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 109340-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 109340-non-native-speakers.pdf
Peer-review Report 109340-peer-reviews.pdf
Scientific Misconduct Check 109340-scientific-misconduct-check.png
Scientific Editor Work List 109340-scientific-editor-work-list.pdf
CrossCheck Report 109340-crosscheck-report.pdf