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Articles Published Processes
8/26/2025 10:18:27 AM | Browse: 61 | Download: 119
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Received |
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2025-05-13 05:17 |
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Peer-Review Started |
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2025-05-14 05:51 |
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First Decision by Editorial Office Director |
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2025-05-22 10:05 |
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Return for Revision |
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2025-05-22 10:05 |
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Revised |
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2025-05-23 07:57 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-07-14 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-14 10:43 |
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Articles in Press |
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2025-07-14 10:43 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-14 09:20 |
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Publish the Manuscript Online |
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2025-08-26 10:18 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Microglial voltage-gated proton channel 1 ablation in diabetic mice mitigates diabetes-driven demyelination and cognitive decline
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Bin Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Top-Level Talents Support Program of Yangzhou University |
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| “Lv Yang Jin Feng” Outstanding Doctor of Yangzhou |
YZLYJFJH2023YXBS169 |
| Natural Science Foundation of Jiangsu Province |
BK20240907 |
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| Corresponding Author |
Bin Li, Full Professor, PhD, Department of Comparative Medicine, Yangzhou University, No. 88 Daxue South Road, Yangzhou 225009, Jiangsu Province, China. lib111701@163.com |
| Key Words |
Neuroinflammation; Demyelination; Microglia; Cognitive dysfunction; Diabetes; Voltage-gated proton channel 1 |
| Core Tip |
Building upon the groundbreaking work by Li et al who demonstrated that microglial voltage-gated proton channel 1 knockout effectively mitigates neuroinflammation, preserves myelin integrity, and rescues memory deficits in diabetic mouse models, our suggestions focus on advancing this research trajectory. We propose implementing longitudinal assessments to track chronic impacts, utilizing cell-type-specific approaches for mechanistic clarity, and pursuing pharmacological translation for therapeutic potential. To systematically guide these efforts, we provide structured tabulated overviews detailing the study's strengths, acknowledging its inherent limitations, and outlining specific strategic research pathways for future investigation. |
| Publish Date |
2025-08-26 10:18 |
| Citation |
Li B. Microglial voltage-gated proton channel 1 ablation in diabetic mice mitigates diabetes-driven demyelination and cognitive decline. World J Psychiatry 2025; 15(9): 109363 |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i9/109363.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i9.109363 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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