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10/14/2025 7:42:37 AM | Browse: 19 | Download: 87
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 109398
Country China
Received
2025-05-12 12:10
Peer-Review Started
2025-05-12 12:11
To Make the First Decision
Return for Revision
2025-07-04 10:18
Revised
2025-07-18 14:56
Second Decision
2025-09-09 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-09 08:12
Articles in Press
2025-09-09 08:12
Publication Fee Transferred
2025-07-19 14:33
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-29 06:12
Publish the Manuscript Online
2025-10-14 07:42
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Lipid metabolic reprogramming in colorectal cancer: Insights to mechanisms and therapeutics
Manuscript Source Unsolicited Manuscript
All Author List Chen-Dong Wang, Bi-Xiang Zhang and Jia Song
ORCID
Author(s) ORCID Number
Jia Song http://orcid.org/0000-0001-6039-6340
Funding Agency and Grant Number
Corresponding Author Jia Song, Associate Professor, Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China. tjhsongjia@hust.edu.cn
Key Words Colorectal cancer; Lipid metabolism reprogramming; High-fat diet; Tumor microenvironment; Targeted drugs
Core Tip Lipid metabolic reprogramming is a hallmark of colorectal cancer, influencing tumor initiation, immune evasion, and therapeutic resistance. Targeting key nodes in lipid synthesis, oxidation, and transport, particularly in combination with immunotherapy, offers a transformative approach to colorectal cancer treatment. While preclinical models highlight the efficacy of metabolic-immune combinatory regimens, future studies should prioritize clinical translation of these strategies while addressing metabolic heterogeneity and microenvironmental crosstalk.
Publish Date 2025-10-14 07:42
Citation <p>Wang CD, Zhang BX, Song J. Lipid metabolic reprogramming in colorectal cancer: Insights to mechanisms and therapeutics. <i>World J Gastrointest Oncol</i> 2025; 17(10): 109398</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i10/109398.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i10.109398
Full Article (PDF) WJGO-17-109398-with-cover.pdf
Manuscript File 109398_Auto_Edited_011753.docx
Answering Reviewers 109398-answering-reviewers.pdf
Audio Core Tip 109398-audio.mp3
Conflict-of-Interest Disclosure Form 109398-conflict-of-interest-statement.pdf
Copyright License Agreement 109398-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 109398-non-native-speakers.pdf
Peer-review Report 109398-peer-reviews.pdf
Scientific Misconduct Check 109398-scientific-misconduct-check.png
Scientific Editor Work List 109398-scientific-editor-work-list.pdf
CrossCheck Report 109398-crosscheck-report.pdf