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Articles Published Processes
9/11/2025 9:41:55 AM | Browse: 316 | Download: 449
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Received |
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2025-05-12 03:01 |
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Peer-Review Started |
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2025-05-13 00:04 |
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First Decision by Editorial Office Director |
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2025-06-06 03:24 |
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Return for Revision |
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2025-06-06 03:24 |
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Revised |
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2025-06-19 14:06 |
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Publication Fee Transferred |
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2025-06-20 10:28 |
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Second Decision by Editor |
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2025-07-17 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-28 08:50 |
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Articles in Press |
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2025-07-28 08:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-03 09:23 |
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Publish the Manuscript Online |
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2025-09-11 09:41 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Observational Study |
| Article Title |
Postprandial C-peptide is more relevant to HbA1c and diabetic microvascular complications than fasting C-peptide in type 2 diabetes
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zheng Wang, Ming-Qun Deng, Li-Xin Guo and Qi Pan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National High Level Hospital Clinical Research Funding |
No. BJ-2022-145 |
| China Endocrinology and Metabolism Young Scientific Talent Research Project |
No. 2021-N-03 |
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| Corresponding Author |
Qi Pan, Professor, Department of Endocrinology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, No. 1 Dahua Road, Dongcheng District, Beijing 100730, China. panqi621@126.com |
| Key Words |
C-peptide; Hemoglobin A1c; Diabetic microvascular complications; Type 2 diabetes mellitus; Observational study |
| Core Tip |
This study highlights postprandial C-peptide (PCP), particularly 2 hours postprandial C-peptide (2hCP)/postprandial blood glucose (PBG), as the strongest predictor of HbA1c in type 2 diabetes mellitus (T2DM), surpassing fasting C-peptide (FCP). Higher CP levels correlate with improved glycemic control. Notably, 2hCP independently reduces the risk of diabetic retinopathy (DR) and diabetic peri-neuropathy (DPN), suggesting that β-cell function preservation benefits both glucose management and complications. These findings advocate prioritizing stimulated CP assessments and exploring 2hCP/PBG as a biomarker for tailored diabetes therapies. |
| Publish Date |
2025-09-11 09:41 |
| Citation |
Wang Z, Deng MQ, Guo LX, Pan Q. Postprandial C-peptide is more relevant to HbA1c and diabetic microvascular complications than fasting C-peptide in type 2 diabetes. World J Diabetes 2025; 16(9): 109414 |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i9/109414.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i9.109414 |
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