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Articles Published Processes
8/20/2025 8:41:24 AM | Browse: 46 | Download: 85
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Received |
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2025-05-12 08:55 |
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Peer-Review Started |
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2025-05-12 08:55 |
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To Make the First Decision |
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Return for Revision |
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2025-05-21 15:15 |
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Revised |
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2025-05-25 14:52 |
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Second Decision |
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2025-07-02 02:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-07-02 06:29 |
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Articles in Press |
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2025-07-02 06:29 |
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Publication Fee Transferred |
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2025-05-26 08:01 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-07 02:48 |
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Publish the Manuscript Online |
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2025-08-20 08:41 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Combination therapy reduces transarterial chemoembolization resistance in advanced hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hu-Yu Jiao, Xin-Mei Yan, Jun-Xin Li and Zhen-Gang Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Zhen-Gang Zhang, MD, PhD, Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430000, Hubei Province, China. zgzhang@tjh.tjmu.edu.cn |
| Key Words |
Transarterial chemoembolization; Programmed death-ligand 1; Molecular targeted therapy; Hepatocellular carcinoma; Drug resistance |
| Core Tip |
This study demonstrates that combining transarterial chemoembolization (TACE) with programmed cell death (ligand) 1 inhibitors and molecular targeted therapy significantly reduces TACE resistance and improves survival in advanced hepatocellular carcinoma. The combination therapy prolongs progression-free survival and overall survival. Additionally, the study identifies maximum tumor diameter, tumor capsule integrity, and bilobar distribution of tumor as key factors influencing TACE resistance, providing new insights for optimizing treatment strategies. |
| Publish Date |
2025-08-20 08:41 |
| Citation |
<p>Jiao HY, Yan XM, Li JX, Zhang ZG. Combination therapy reduces transarterial chemoembolization resistance in advanced hepatocellular carcinoma. <i>World J Clin Oncol</i> 2025; 16(8): 109419</p> |
| URL |
https://www.wjgnet.com/2218-4333/full/v16/i8/109419.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v16.i8.109419 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
