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12/23/2025 8:03:21 AM | Browse: 5 | Download: 15
Publication Name World Journal of Nephrology
Manuscript ID 109457
Country Australia
Received
2025-05-12 02:38
Peer-Review Started
2025-05-13 00:03
First Decision by Editorial Office Director
2025-05-30 02:49
Return for Revision
2025-05-30 02:49
Revised
2025-06-23 00:42
Publication Fee Transferred
Second Decision by Editor
2025-09-26 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-09-26 08:49
Articles in Press
2025-09-26 08:49
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-15 08:30
Publish the Manuscript Online
2025-12-23 08:03
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Minireviews
Article Title Cardio-kidney-metabolic protective effects of semaglutide across the spectrum of chronic kidney disease
Manuscript Source Invited Manuscript
All Author List Harry Economos and Richard J MacIsaac
ORCID
Author(s) ORCID Number
Harry Economos http://orcid.org/0009-0000-1872-8241
Richard J MacIsaac http://orcid.org/0000-0001-8058-6977
Funding Agency and Grant Number
Corresponding Author Richard J MacIsaac, Director, Professor, Department of Endocrinology and Diabetes, St Vincent's Hospital Melbourne, 4th Floor, Daly Wing, 35 Victoria Parade, PO Box 2900, Fitzroy 3065, Victoria, Australia. r.macisaac@unimelb.edu.au
Key Words Albuminuria; Diabetes; Chronic kidney disease; Glucagon-like peptide-1 receptor agonist; Semaglutide
Core Tip In people with type 2 diabetes and chronic kidney disease, semaglutide, saves kidneys, hearts and lives. The glucagon-like peptide-1 receptor agonist (GLP-1RA) class of medications are now being proposed as the fourth pillar of diabetic kidney disease therapy, along with renin-angiotensin-aldosterone system blocking agents, sodium glucose co-transporter-2 inhibitors, and finerenone. We await definitive evidence to support a kidney protective effect of GLP-1RAs outside of the setting of diabetes.
Publish Date 2025-12-23 08:03
Citation

Economos H, MacIsaac RJ. Cardio-kidney-metabolic protective effects of semaglutide across the spectrum of chronic kidney disease. World J Nephrol 2025; 14(4): 109457

URL https://www.wjgnet.com/2220-6124/full/v14/i4/109457.htm
DOI https://dx.doi.org/10.5527/wjn.v14.i4.109457
Full Article (PDF) WJN-14-109457-with-cover.pdf
Manuscript File 109457_Auto_Edited_033944.docx
Answering Reviewers 109457-answering-reviewers.pdf
Audio Core Tip 109457-audio.m4a
Conflict-of-Interest Disclosure Form 109457-conflict-of-interest-statement.pdf
Copyright License Agreement 109457-copyright-assignment.pdf
Peer-review Report 109457-peer-reviews.pdf
Scientific Misconduct Check 109457-scientific-misconduct-check.png
Scientific Editor Work List 109457-scientific-editor-work-list.pdf
CrossCheck Report 109457-crosscheck-report.pdf