BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/24/2025 9:01:53 AM | Browse: 56 | Download: 21
 |
Received |
|
2025-05-14 02:52 |
|
Peer-Review Started |
|
2025-05-14 02:52 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2025-05-22 09:55 |
|
Revised |
|
2025-06-04 18:36 |
|
Second Decision |
|
2025-07-18 02:43 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2025-07-18 05:35 |
|
Articles in Press |
|
2025-07-18 05:35 |
|
Publication Fee Transferred |
|
2025-06-09 11:32 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-09-09 05:59 |
|
Publish the Manuscript Online |
|
2025-09-24 09:01 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Case Control Study |
| Article Title |
Gallstone and bile microbiota: A case-control study based on 16S rRNA gene sequencing
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhong-Xiao Lu, Yan-Qi Jiang, Dang-Shou Wang, Yu-Ting Song, Xiao-Ming Jiang, Fu-Jian Xu, Jie Tang, Bing Li and Wen-Hai Huang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Youth Scientific Research Launch Fund Project of Jinshan Hospital, Affiliated with Fudan University |
No. JYQN-LC-202214 |
|
| Corresponding Author |
Bing Li, Researcher, Research Center for Clinical Medicine, Jinshan Hospital, Fudan University, No. 1508 Longhang Road, Shanghai 201508, China. li_bing@fudan.edu.cn |
| Key Words |
Gallstones; Bile microbiota; 16S rRNA sequencing; Diversity analysis; Genus identification |
| Core Tip |
This retrospective study analyzed bile microbiota composition in 40 patients. Results demonstrated that samples from gallstone patients exhibited significantly reduced overall microbial diversity alongside a striking dominance of Proteobacteria. In contrast, bile samples from gallstone-free individuals showed relative enrichment in health-associated genera, including protective taxa like Lactobacillus. The findings indicate that dysbiosis within the bile microbiome, particularly the overgrowth of Proteobacteria, actively drives gallstone pathogenesis. This suggests that modulating the bile microbiota represents a promising novel therapeutic avenue for gallstone prevention or treatment through targeted interventions. |
| Publish Date |
2025-09-24 09:01 |
| Citation |
<p>Lu ZX, Jiang YQ, Wang DS, Song YT, Jiang XM, Xu FJ, Tang J, Li B, Huang WH. Gallstone and bile microbiota: A case-control study based on 16S rRNA gene sequencing. <i>World J Gastrointest Surg</i> 2025; 17(9): 109521</p> |
| URL |
https://www.wjgnet.com/1948-9366/full/v17/i9/109521.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v17.i9.109521 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
