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9/23/2025 6:48:57 AM | Browse: 56 | Download: 93
Publication Name World Journal of Clinical Oncology
Manuscript ID 109554
Country China
Received
2025-05-15 06:55
Peer-Review Started
2025-05-15 06:58
First Decision by Editorial Office Director
2025-06-04 01:59
Return for Revision
2025-06-04 01:59
Revised
2025-06-13 02:39
Publication Fee Transferred
Second Decision by Editor
2025-07-09 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-07-09 08:21
Articles in Press
2025-07-09 08:21
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-03 08:13
Publish the Manuscript Online
2025-09-23 06:48
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Modified predictive model incorporating the waist-to-hip ratio for advanced colorectal neoplasia: A step toward precision screening
Manuscript Source Invited Manuscript
All Author List Zong-Xian Zhao and Zong-Ju Hu
ORCID
Author(s) ORCID Number
Zong-Xian Zhao http://orcid.org/0000-0001-7553-2085
Zong-Ju Hu http://orcid.org/0009-0002-0136-5979
Funding Agency and Grant Number
Corresponding Author Zong-Ju Hu, Department of Anorectal Surgery, Fuyang People’s Hospital, No. 501 Sanqing Road, Yingzhou District, Fuyang 236000, Anhui Province, China. hzj130123@126.com
Key Words Advanced colorectal neoplasia; Abdominal obesity; Colorectal cancer screening; Risk scoring model; Waist-to-hip ratio
Core Tip The new Asia-Pacific Colorectal Screening model, by incorporating the waist-to-hip ratio (WHR), better captures the metabolic risks driven by visceral fat and significantly improves the prediction accuracy. A high WHR (> 0.9 for men; > 0.85 for women) increases the risk of advanced colorectal neoplasms by 46%, enabling high-risk subgroups to receive prioritized colonoscopy. Future research should be expanded to multi-regional cohorts and incorporate more biomarkers (such as percentage of body fat, blood lipid and blood glucose levels), laboratory (stool DNA, polygenic risk scores, circulating tumor DNA) and imaging indicators (computed tomography-measured visceral fat area) to optimize the model.
Publish Date 2025-09-23 06:48
Citation

Zhao ZX, Hu ZJ. Modified predictive model incorporating the waist-to-hip ratio for advanced colorectal neoplasia: A step toward precision screening. World J Clin Oncol 2025; 16(9): 109554

URL https://www.wjgnet.com/2218-4333/full/v16/i9/109554.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i9.109554
Full Article (PDF) WJCO-16-109554-with-cover.pdf
Manuscript File 109554_Auto_Edited_065633.docx
Answering Reviewers 109554-answering-reviewers.pdf
Audio Core Tip 109554-audio.m4a
Conflict-of-Interest Disclosure Form 109554-conflict-of-interest-statement.pdf
Copyright License Agreement 109554-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 109554-non-native-speakers.pdf
Peer-review Report 109554-peer-reviews.pdf
Scientific Misconduct Check 109554-scientific-misconduct-check.png
Scientific Editor Work List 109554-scientific-editor-work-list.pdf
CrossCheck Report 109554-crosscheck-report.pdf