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11/4/2025 2:41:54 AM | Browse: 13 | Download: 54
Publication Name World Journal of Psychiatry
Manuscript ID 109581
Country United States
Received
2025-05-15 01:49
Peer-Review Started
2025-05-26 00:08
To Make the First Decision
Return for Revision
2025-05-29 08:16
Revised
2025-06-09 20:08
Second Decision
2025-09-22 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-22 09:32
Articles in Press
2025-09-22 09:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-21 09:31
Publish the Manuscript Online
2025-11-04 02:41
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Minireviews
Article Title Agitation in Alzheimer’s disease: From assessment to therapeutics
Manuscript Source Invited Manuscript
All Author List Antonio L Teixeira, Youngran Kim, Thiago M Cordeiro, Gabriel A de Erausquin and Natalia P Rocha
ORCID
Author(s) ORCID Number
Antonio L Teixeira http://orcid.org/0000-0002-9621-5422
Youngran Kim http://orcid.org/0000-0002-2063-5017
Thiago M Cordeiro http://orcid.org/0000-0003-4933-6309
Gabriel A de Erausquin http://orcid.org/0000-0001-6423-4461
Natalia P Rocha http://orcid.org/0000-0003-2616-8082
Funding Agency and Grant Number
Funding Agency Grant Number
National Institutes of Health/National Institute on Aging No. 1R21AG091282
Corresponding Author Antonio L Teixeira, Biggs Institute, The University of Texas Health Science Center at San Antonio, 8300 Floyd Curl Drive, San Antonio, TX 78229, United States. altexr@gmail.com
Key Words Alzheimer’s disease; Dementia; Agitation; Aggression; Antipsychotics; Antidepressants
Core Tip In Alzheimer’s disease, agitation is a clinically relevant neuropsychiatric syndrome managed by non-pharmacological and pharmacological approaches. Ruling out delirium, identifying and addressing environmental triggers (e.g., change in caregiver) are fundamental therapeutic steps. Antipsychotics (e.g., brexpiprazole, risperidone) are commonly used in acute agitation, especially in the context of potential harm to self and others. For chronic agitation, serotonin-selective reuptake inhibitors (e.g., escitalopram) are preferred.
Publish Date 2025-11-04 02:41
Citation <p>Teixeira AL, Kim Y, Cordeiro TM, de Erausquin GA, Rocha NP. Agitation in Alzheimer’s disease: From assessment to therapeutics. <i>World J Psychiatry</i> 2025; 15(11): 109581</p>
URL https://www.wjgnet.com/2220-3206/full/v15/i11/109581.htm
DOI https://dx.doi.org/10.5498/wjp.v15.i11.109581
Full Article (PDF) WJP-15-109581-with-cover.pdf
Manuscript File 109581_Auto_Edited_055104.docx
Answering Reviewers 109581-answering-reviewers.pdf
Audio Core Tip 109581-audio.mp3
Conflict-of-Interest Disclosure Form 109581-conflict-of-interest-statement.pdf
Copyright License Agreement 109581-copyright-assignment.pdf
Supplementary Material 109581-supplementary-material.pdf
Peer-review Report 109581-peer-reviews.pdf
Scientific Misconduct Check 109581-scientific-misconduct-check.png
Scientific Editor Work List 109581-scientific-editor-work-list.pdf
CrossCheck Report 109581-crosscheck-report.pdf