BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/23/2025 6:48:57 AM | Browse: 43 | Download: 30
 |
Received |
|
2025-05-19 14:53 |
|
Peer-Review Started |
|
2025-05-19 14:53 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2025-06-05 09:38 |
|
Revised |
|
2025-06-15 03:12 |
|
Second Decision |
|
2025-07-09 02:39 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2025-07-09 08:05 |
|
Articles in Press |
|
2025-07-09 08:05 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-08-28 08:36 |
|
Publish the Manuscript Online |
|
2025-09-23 06:48 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Editorial |
| Article Title |
Swollen lymph node metastasis in gastric cancer: A forgotten prognostic signal in need of clinical action
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Keykavous Parang and Amir Nasrolahi Shirazi |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Keykavous Parang, PharmD, PhD, Tenured Professor, Department of Biomedical and Pharmaceutical Sciences, Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, No. 9401 Jeronimo Road, Irvine, CA 92618, United States, 9401 Jeronimo Road, Chapman University, School of Pharmacy, Irvine, CA 92618, USA. parang@chapman.edu., Irvine, California 92618, United States. parang@chapman.edu |
| Key Words |
Gastric cancer; Lymph node metastasis; Neoadjuvant chemotherapy; Precision oncology; Prognosis; Staging; Swollen lymph node |
| Core Tip |
Swollen lymph node metastasis (SLNM), defined by bulky nodal tumor deposits (> 3 cm on imaging or multiple > 1.5 cm nodes) in gastric cancer, confers a dramatically worse outcome. In a large recent cohort, SLNM was independently associated with approximately 50% higher mortality risk. This editorial emphasizes SLNM’s under-recognized prognostic value. Formally incorporating SLNM into gastric cancer staging and treatment algorithms (for example, prioritizing neoadjuvant chemotherapy) may improve risk stratification. Recognizing SLNM as a biomarker can enhance precision oncology approaches by identifying patients for intensified multimodal therapy. |
| Publish Date |
2025-09-23 06:48 |
| Citation |
<p>Parang K, Shirazi AN. Swollen lymph node metastasis in gastric cancer: A forgotten prognostic signal in need of clinical action. <i>World J Clin Oncol</i> 2025; 16(9): 109711</p> |
| URL |
https://www.wjgnet.com/2218-4333/full/v16/i9/109711.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v16.i9.109711 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
