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Articles Published Processes
1/14/2026 8:39:28 AM | Browse: 2 | Download: 0
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Received |
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2025-05-20 07:00 |
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Peer-Review Started |
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2025-05-21 00:37 |
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First Decision by Editorial Office Director |
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2025-05-30 03:31 |
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Return for Revision |
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2025-05-30 03:31 |
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Revised |
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2025-06-07 22:29 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-08-14 03:14 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-15 01:04 |
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Articles in Press |
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2025-08-15 01:04 |
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Edit the Manuscript by Language Editor |
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2025-08-19 01:25 |
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Typeset the Manuscript |
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2025-10-31 14:35 |
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Publish the Manuscript Online |
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2026-01-14 08:39 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Editorial |
| Article Title |
Bridging gaps in corneal ulcer management: Can photoactivated chromophore for infectious keratitis–corneal collagen cross-linking delay or replace therapeutic keratoplasty?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Niki I Antonopoulou, Maria S Spyropoulou, Stavros P Papadakos, Garyfalia N Papavasileiou and Andreas C Dimakis |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Stavros P Papadakos, First Department of Gastroenterology, National and Kapodistrian University of Athens, General Hospital of Athens "Laiko", 17 Agiou Thoma Street, Goudi, Athens 11527, Greece. stavrospapadakos@gmail.com |
| Key Words |
Infectious keratitis; Photoactivated chromophore for infectious keratitis–corneal collagen cross-linking; corneal ulcer; therapeutic keratoplasty; cross-linking therapy |
| Core Tip |
Infectious keratitis remains a major cause of corneal blindness, particularly in low-resource settings where delayed presentation and limited access to donor tissue challenge effective management. This editorial highlight the potential of photoactivated chromophore for infectious keratitis–corneal collagen cross-linking (PACK-CXL) as an adjunct or alternative to therapeutic penetrating keratoplasty (PK). With both antimicrobial and tissue-stabilizing properties, PACK-CXL offers a globe-sparing approach that may reduce the need for PK. Integrating PACK-CXL into a stratified treatment algorithm based on ulcer severity and etiology could improve outcomes and expand access to vision-saving care. |
| Publish Date |
2026-01-14 08:39 |
| Citation |
Antonopoulou NI, Spyropoulou MS, Papadakos SP, Papavasileiou GN, Dimakis AC. Bridging gaps in corneal ulcer management: Can photoactivated chromophore for infectious keratitis–corneal collagen cross-linking delay or replace therapeutic keratoplasty? World J Transplant 2026; 16(1): 109740 |
| URL |
https://www.wjgnet.com/2220-3230/full/v16/i1/109740.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v16.i1.109740 |
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