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10/14/2025 7:42:35 AM | Browse: 13 | Download: 61
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 109744
Country China
Received
2025-05-21 06:24
Peer-Review Started
2025-05-21 06:24
To Make the First Decision
Return for Revision
2025-06-05 08:21
Revised
2025-07-07 06:12
Second Decision
2025-08-25 03:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-25 09:53
Articles in Press
2025-08-25 09:53
Publication Fee Transferred
2025-07-09 12:33
Edit the Manuscript by Language Editor
2025-09-01 22:14
Typeset the Manuscript
2025-10-09 00:10
Publish the Manuscript Online
2025-10-14 07:42
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Helicobacter pylori-induced miR-136 is a potential predictor of early-stage gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Tao Chen, An-Qiang Feng, Xiao-Ran Shen, Ni-Yi Dang, Feng Ye and Guo-Xin Zhang
ORCID
Author(s) ORCID Number
Guo-Xin Zhang http://orcid.org/0009-0000-9314-9071
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82470593
General Project of the Development Fund of the Affiliated Hospital of Xuzhou Medical University XYFM202334
Corresponding Author Guo-Xin Zhang, PhD, Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, No. 199 Jiefang South Road, Nanjing 210029, Jiangsu Province, China. nanjingmedical@163.com
Key Words Helicobacter pylori; Gastric cancer; miR-136; Nuclear factor kappa-B; PDCD11
Core Tip Helicobacter pylori infection upregulates miR-136, promoting gastric cancer progression by suppressing PDCD11 via nuclear factor kappa-B (NF-κB) activation. This study identifies miR-136 as a potential diagnostic biomarker and therapeutic target for early-stage gastric cancer, demonstrating its role in tumor growth and metastasis through in vitro and in vivo models. Targeting the NF-κB/miR-136/PDCD11 axis may offer new strategies for intervention.
Publish Date 2025-10-14 07:42
Citation <p>Chen T, Feng AQ, Shen XR, Dang NY, Ye F, Zhang GX. Helicobacter pylori-induced miR-136 is a potential predictor of early-stage gastric cancer. <i>World J Gastrointest Oncol</i> 2025; 17(10): 109744</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i10/109744.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i10.109744
Full Article (PDF) WJGO-17-109744-with-cover.pdf
The ARRIVE Guidelines 109744-The-ARRIVE-Guidelines.pdf
Manuscript File 109744_Auto_Edited_085303.docx
Answering Reviewers 109744-answering-reviewers.pdf
Audio Core Tip 109744-audio.mp3
Biostatistics Review Certificate 109744-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 109744-conflict-of-interest-statement.pdf
Copyright License Agreement 109744-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 109744-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document 109744-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 109744-non-native-speakers.pdf
Peer-review Report 109744-peer-reviews.pdf
Scientific Misconduct Check 109744-scientific-misconduct-check.png
Scientific Editor Work List 109744-scientific-editor-work-list.pdf
CrossCheck Report 109744-crosscheck-report.pdf