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Articles Published Processes
10/27/2025 10:57:54 AM | Browse: 35 | Download: 48
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Received |
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2025-05-20 07:19 |
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Peer-Review Started |
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2025-05-21 00:08 |
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To Make the First Decision |
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Return for Revision |
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2025-05-24 02:51 |
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Revised |
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2025-06-04 16:02 |
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Second Decision |
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2025-09-22 02:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-22 09:34 |
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Articles in Press |
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2025-09-22 09:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-16 08:23 |
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Publish the Manuscript Online |
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2025-10-27 10:57 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Current clinical research status and future treatment directions for liver cirrhosis combined with portal vein thrombosis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Wen-Long He, Shuai Yan, Jia-Jie Lu, Lin Chen and Jin-Zhu Wu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jin-Zhu Wu, Chief Physician, MD, Professor, Department of Hepatobiliary Surgery, Nantong Third People’s Hospital, No. 19 Qixiu Road, Chongchuan District, Nantong 226300, Jiangsu Province, China. wjz1258@163.com |
| Key Words |
Liver cirrhosis; Portal vein thrombosis; Anticoagulation; Edoxaban; Direct-acting oral anticoagulants; Portal hypertension; Thrombolysis |
| Core Tip |
Portal vein thrombosis represents a significant complication of liver cirrhosis and contributes to the exacerbation of portal hypertension and results in severe clinical outcomes including oesophageal variceal bleeding and refractory ascites. This review presents a comprehensive overview of the aetiology, diagnosis, clinical manifestations, and treatment options for portal vein thrombosis in cirrhotic patients. Furthermore, this highlights the emerging role of direct oral anticoagulants, such as edoxaban, which offer promising therapeutic potential because of their efficacy, safety, and convenience. Future research should address individualized treatment strategies to optimize the balance between anticoagulation benefits and bleeding risks, which improves patient prognosis. |
| Publish Date |
2025-10-27 10:57 |
| Citation |
<p>He WL, Yan S, Lu JJ, Chen L, Wu JZ. Current clinical research status and future treatment directions for liver cirrhosis combined with portal vein thrombosis. <i>World J Hepatol</i> 2025; 17(10): 109745</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i10/109745.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i10.109745 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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