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11/28/2025 2:00:43 PM | Browse: 9 | Download: 11
Publication Name World Journal of Critical Care Medicine
Manuscript ID 109786
Country Singapore
Received
2025-05-22 06:58
Peer-Review Started
2025-05-22 06:58
First Decision by Editorial Office Director
2025-06-12 01:33
Return for Revision
2025-06-12 01:33
Revised
2025-06-17 09:01
Publication Fee Transferred
2025-06-27 02:55
Second Decision by Editor
2025-08-20 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-08-20 11:14
Articles in Press
2025-08-20 11:14
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-13 06:59
Publish the Manuscript Online
2025-11-28 14:00
ISSN 2220-3141(online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Case Report
Article Title Thrombotic storm presenting with synchronous myocardial infarction, stroke and bowel ischaemia: A case report
Manuscript Source Unsolicited Manuscript
All Author List Wen-Jian Chan, Timothy Xin Zhong Tan, R Ponampalam and Arjun Thompson
ORCID
Author(s) ORCID Number
Wen-Jian Chan http://orcid.org/0009-0009-3888-5901
Timothy Xin Zhong Tan http://orcid.org/0000-0001-5938-2304
R Ponampalam http://orcid.org/0000-0002-5813-2044
Funding Agency and Grant Number
Corresponding Author Wen-Jian Chan, Department of Emergency Medicine, SingHealth, SINGAPORE GENERAL HOSPITAL Outram Road Singapore 169608, Singapore 169608, Singapore. chan.wenjian@gmail.com
Key Words Case report; Ischaemic bowel; Acute myocardial infarct; Stroke; Thrombosis
Core Tip This case describes the first known instance of simultaneous myocardial infarction, stroke, and bowel infarction, likely due to a thrombotic crisis. Synchronous cardiocerebral infarcts are rare (0.009%–0.29%) and typically affect older males. Etiology remains unclear but may involve cardiogenic shock reducing cerebral perfusion. Management requires a multidisciplinary approach. If within the thrombolysis window (4.5 hours), IV recombinant tissue plasminogen activator (0.9 mg/kg) should be given first, followed by coronary intervention. Outside this window, treatment prioritization depends on hemodynamic stability—cardiac intervention for shock, stroke management otherwise. Post-acute care involves high-dose statins if atherosclerosis is suspected and close monitoring in a high-acuity setting.
Publish Date 2025-11-28 14:00
Citation

Chan WJ, Tan TXZ, Ponampalam R, Thompson A. Thrombotic storm presenting with synchronous myocardial infarction, stroke and bowel ischaemia: A case report. World J Crit Care Med 2025; 14(4): 109786

URL https://www.wjgnet.com/2220-3141/full/v14/i4/109786.htm
DOI https://dx.doi.org/10.5492/wjccm.v14.i4.109786
Full Article (PDF) WJCCM-14-109786-with-cover.pdf
CARE Checklist–2016 109786-CARE-Checklist-2016.pdf
Manuscript File 109786_Auto_Edited_032349.docx
Answering Reviewers 109786-answering-reviewers.pdf
Audio Core Tip 109786-audio.mp3
Conflict-of-Interest Disclosure Form 109786-conflict-of-interest-statement.pdf
Copyright License Agreement 109786-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 109786-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 109786-non-native-speakers.pdf
Peer-review Report 109786-peer-reviews.pdf
Scientific Misconduct Check 109786-scientific-misconduct-check.png
Scientific Editor Work List 109786-scientific-editor-work-list.pdf
CrossCheck Report 109786-crosscheck-report.pdf