| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Incidence, disease course, therapeutic strategies and outcomes of inflammatory bowel diseases-unclassified patients in Western Hungary: A population-based cohort
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Fruzsina Balogh, Lorant Gonczi, Dorottya Angyal, Petra Anna Golovics, Tunde Pandur, Gyula David, Zsuzsanna Erdelyi, Istvan Szita, Akos Ilias, Laszlo Lakatos and Peter Laszlo Lakatos |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Peter Laszlo Lakatos, PhD, Professor, Division of Gastroenterology & Hepatology, McGill University, 1650 Avenue Cedar, Montreal H3A0G4, Quebec, Canada. kislakpet99@gmail.com |
| Key Words |
Crohn’s disease; Ulcerative colitis; Inflammatory bowel disease unclassified; Population-based; Outcomes; Medical therapy; Resective surgery |
| Core Tip |
This is the one of the first comprehensive, population-based study from Eastern Europe evaluating the long-term incidence, disease progression, and outcomes of unclassified inflammatory bowel disease (IBD-U). Analyzing data from 119 patients over four decades, we identified a high rate of reclassification to Crohn’s disease and substantial use of biological therapies and surgeries, reflecting a more severe disease phenotype than previously reported. These findings challenge the notion of IBD-U as a benign or transitional diagnosis and underscore the need for tailored therapeutic strategies and further longitudinal research. |
| Publish Date |
2025-09-01 08:05 |
| Citation |
<p>Balogh F, Gonczi L, Angyal D, Golovics PA, Pandur T, David G, Erdelyi Z, Szita I, Ilias A, Lakatos L, Lakatos PL. Incidence, disease course, therapeutic strategies and outcomes of inflammatory bowel diseases-unclassified patients in Western Hungary: A population-based cohort. <i>World J Gastroenterol</i> 2025; 31(33): 109800</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i33/109800.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i33.109800 |
