| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Retrospective Study |
| Article Title |
Important role of tumor deposits and negative lymph nodes in prognosis of N1c colorectal cancer patients
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Gang Sun, Shao-Xuan Chen, Bai-Long Sun, Da-Kui Zhang, Ding-Rong Zhong, Tong-Yin Zhang, Yu-Wan Hu, Zi-Han Han, Wen-Xiao Wu, Zhi-Yong Hou, Li Yao, Ya-Jun Zhang, Hong-Liang Sun and Jian-Zheng Jie |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National High Level Hospital Clinical Research Funding |
No. 2023-NHLHCRF-BQ-32 |
| National Key Research and Development Program of China |
No. 2024YFE0198300 |
| National High Level Hospital Clinical Research Funding |
No. 2023-NHLHCRF-YYPPLC-ZR-13 |
| Beijing Municipal Natural Science Foundation |
No. 7222316 |
|
| Corresponding Author |
Jian-Zheng Jie, Department of General Surgery, China-Japan Friendship Hospital, No. 2 Yinghuayuan East Street, Chaoyang District, Beijing 100029, China. jianzhengjie@sohu.com |
| Key Words |
Colorectal cancer; N1c stage; Negative lymph node; Tumor deposits; Prognosis |
| Core Tip |
To evaluate the combination of tumor deposits (TDs) and negative lymph node (NLN) as potential prognostic indicators in N1c colorectal cancer (CRC). We retrospectively identified 107 consecutive patients who had CRC with N1c disease. There was no significant difference in prognosis between patients with more than 12 NLN or not for disease free survival, the same result could be seen according to the number of TD. The definition of combination of TD and NLN (NLNTD) = NLN/(TD + 1) with cutoff value as 6 could divide patients into two groups with different prognosis for disease free survival. These two groups had different prognosis without perineural invasion or lymphovascular invasion even neither. |
| Publish Date |
2025-08-18 10:04 |
| Citation |
<p>Sun ZG, Chen SX, Sun BL, Zhang DK, Zhong DR, Zhang TY, Hu YW, Han ZH, Wu WX, Hou ZY, Yao L, Zhang YJ, Sun HL, Jie JZ. Important role of tumor deposits and negative lymph nodes in prognosis of N1c colorectal cancer patients. <i>World J Gastroenterol</i> 2025; 31(31): 109857</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i31/109857.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i31.109857 |
