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Articles Published Processes
12/22/2025 7:43:01 AM | Browse: 71 | Download: 249
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Received |
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2025-05-26 13:40 |
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Peer-Review Started |
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2025-05-26 13:40 |
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First Decision by Editorial Office Director |
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2025-07-08 08:21 |
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Return for Revision |
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2025-07-08 08:21 |
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Revised |
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2025-07-12 02:40 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-30 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-30 10:07 |
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Articles in Press |
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2025-10-30 10:07 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-08 07:04 |
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Publish the Manuscript Online |
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2025-12-22 07:43 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Metabolic changes after hepatectomy: Implications for perioperative management and long-term outcomes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Joshua Zhuo Lee, Sandra Joanne Kar Kwan Ng and Vishal G Shelat |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Vishal G Shelat, Adjunct Associate Professor, FRCS, Department of General Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore, Singapore. vgshelat@gmail.com |
| Key Words |
Energy consumption; Glucose metabolism; Hepatectomy; Ischemic reperfusion injury; Lipid metabolism; Liver regeneration; Liver resection; Oxygen consumption; Physiologic pringle manoeuvre; Protein metabolism |
| Core Tip |
This narrative review explores the intricate metabolic adaptations following hepatectomy, emphasising the shift towards gluconeogenesis and transient insulin resistance, increased lipid oxidation, imbalance in amino acids, and a heightened inflammatory response (especially in ischaemic reperfusion injury). It highlights the role of the liver in maintaining systemic metabolic homeostasis, and how surgical disruption affects liver metabolism. Metabolic changes post-hepatectomy influence recovery, and may serve as targets for optimising recovery, thereby guiding and enhancing perioperative care and ultimately improving surgical outcomes. |
| Publish Date |
2025-12-22 07:43 |
| Citation |
Lee JZ, Ng SJKK, Shelat VG. Metabolic changes after hepatectomy: Implications for perioperative management and long-term outcomes. World J Gastrointest Pathophysiol 2025; 16(4): 109860 |
| URL |
https://www.wjgnet.com/2150-5330/full/v16/i4/109860.htm |
| DOI |
https://dx.doi.org/10.4291/wjgp.v16.i4.109860 |
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