Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	109884
Country	China

Received	2025-05-26 08:22
Peer-Review Started	2025-05-26 08:22
To Make the First Decision
Return for Revision	2025-05-28 09:40
Revised	2025-06-17 08:50
Second Decision	2025-07-14 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-14 08:35
Articles in Press	2025-07-14 08:35
Publication Fee Transferred	2025-06-19 08:26
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-08-07 06:32
Publish the Manuscript Online	2025-08-25 12:36

ISSN	1948-9366 (online)
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Category	Imaging Science & Photographic Technology
Manuscript Type	Observational Study
Article Title	Changes in liver and spleen stiffness after transjugular intrahepatic portosystemic shunt and their relationship with prognosis
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Fang Liu, Xiao-Chun Huang, Qian-Jun Ye, Li-Jing Yuan, Gui-Fang Gao, Jin-Yu Li and Dui-Ping Feng
ORCID	Author(s) ORCID Number Xiao-Chun Huang http://orcid.org/0000-0003-1835-3368 Qian-Jun Ye http://orcid.org/0000-0002-0997-5395 Jin-Yu Li http://orcid.org/0000-0003-2563-5937 Dui-Ping Feng http://orcid.org/0000-0003-4516-3797
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82200650 Shanxi Provincial Clinical Research Center for Interventional Medicine 202204010501004 the Precision Interventional Diagnosis and Treatment Technology Innovation Base for Cirrhosis and Portal Hypertension YDZJSX20231B010 the Natural Science Foundation of Shanxi Province 20210302124282, 202203021212046 the Shanxi Province Higher Education “Billion Project Science and Technology Guidance Project” 2C622024120 the National Natural Science Foundation of China Supporting Fund Y82200650
Corresponding Author	Dui-Ping Feng, Chief Physician, Department of Oncological and Vascular Intervention, First Hospital of Shanxi Medical University, No. 85 Jiefang South Road, Yingze District, Taiyuan 030001, Shanxi Province, China. fengdp@sxmu.edu.cn
Key Words	Liver and spleen stiffness; Sound touch quantify; Portal pressure gradient; Transjugular intrahepatic portosystemic shunt; Prognosis
Core Tip	This study involved 76 patients with liver cirrhosis who underwent a transjugular intrahepatic portosystemic shunt (TIPS). The stiffness of the liver and spleen was assessed using point shear wave elastography with ultrasonic imaging, which quantifies the sound touch value. The results indicated that spleen stiffness significantly decreased over time following TIPS. Older age and higher liver stiffness were correlated with an elevated risk of mortality following TIPS. In summary, following TIPS, spleen stiffness exhibited a more pronounced change than liver stiffness. Preoperative liver stiffness serves as a prognostic indicator for survival in patients undergoing TIPS.
Publish Date	2025-08-25 12:36
Citation	<p>Liu XF, Huang XC, Ye QJ, Yuan LJ, Gao GF, Li JY, Feng DP. Changes in liver and spleen stiffness after transjugular intrahepatic portosystemic shunt and their relationship with prognosis. <i>World J Gastrointest Surg</i> 2025; 17(8): 109884</p>
URL	https://www.wjgnet.com/1948-9366/full/v17/i8/109884.htm
DOI	https://dx.doi.org/10.4240/wjgs.v17.i8.109884

Full Article (PDF)	WJGS-17-109884-with-cover.pdf
STROBE Statement	109884-STROBE-statement.pdf
Manuscript File	109884_Auto_Edited_070519.docx
Answering Reviewers	109884-answering-reviewers.pdf
Audio Core Tip	109884-audio.mp3
Biostatistics Review Certificate	109884-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	109884-conflict-of-interest-statement.pdf
Copyright License Agreement	109884-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	109884-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	109884-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	109884-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	109884-non-native-speakers.pdf
Supplementary Material	109884-supplementary-material.pdf
Peer-review Report	109884-peer-reviews.pdf
Scientific Misconduct Check	109884-scientific-misconduct-check.png
Scientific Editor Work List	109884-scientific-editor-work-list.pdf
CrossCheck Report	109884-crosscheck-report.pdf