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Articles Published Processes
10/25/2025 1:11:36 AM | Browse: 17 | Download: 34
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Received |
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2025-06-27 10:01 |
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Peer-Review Started |
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2025-06-27 10:01 |
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To Make the First Decision |
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Return for Revision |
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2025-07-21 08:20 |
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Revised |
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2025-07-28 10:01 |
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Second Decision |
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2025-09-15 00:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-22 07:07 |
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Articles in Press |
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2025-09-22 07:07 |
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Publication Fee Transferred |
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2025-07-30 09:54 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-15 07:35 |
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Publish the Manuscript Online |
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2025-10-25 01:11 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Otorhinolaryngology |
| Manuscript Type |
Prospective Study |
| Article Title |
Long-term follow-up of autologous nasal epithelial stem cell transplantation for congenital olfactory disorders in children
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xia Ni, Jie Shi, Jian Ning and Xiao-Ling Tian |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Hangzhou Medical and Health Technology Project |
B20210443 |
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| Corresponding Author |
Xiao-Ling Tian, Department of Otolaryngology, Hangzhou Linping District Integrated Traditional Chinese and Western Medicine Hospital, No. 15 Baojian Road, Linping District, Hangzhou 311100, Zhejiang Province, China. xiang19257489868@163.com |
| Key Words |
Congenital anosmia; Stem cell therapy; Olfactory dysfunction; Pediatric otolaryngology; Regenerative medicine |
| Core Tip |
This prospective study evaluated the long-term outcomes of autologous nasal epithelial stem cell transplantation in children with congenital olfactory disorders. Fifty pediatric patients were followed for 3 years, demonstrating significant improvements in olfactory function, electro-olfactogram readings, and quality of life scores. The treatment was well-tolerated, with only minor, self-limiting complications reported. Age at intervention and baseline residual function were positively associated with better outcomes. These findings offer promising evidence for a novel regenerative approach to pediatric anosmia, addressing a critical gap in current treatment options and paving the way for broader clinical application. |
| Publish Date |
2025-10-25 01:11 |
| Citation |
<p>Ni X, Shi J, Ning J, Tian XL. Long-term follow-up of autologous nasal epithelial stem cell transplantation for congenital olfactory disorders in children. <i>World J Stem Cells</i> 2025; 17(10): 109942</p> |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i10/109942.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i10.109942 |
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