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9/24/2025 9:02:04 AM | Browse: 71 | Download: 46
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 110034
Country China
Received
2025-05-28 04:19
Peer-Review Started
2025-05-28 04:19
To Make the First Decision
Return for Revision
2025-06-17 02:37
Revised
2025-06-30 07:38
Second Decision
2025-08-04 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-04 07:08
Articles in Press
2025-08-04 07:08
Publication Fee Transferred
2025-07-02 09:08
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-29 03:04
Publish the Manuscript Online
2025-09-24 09:02
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Randomized Controlled Trial
Article Title Remimazolam reduces State-Trait Anxiety Inventory-State Scale scores in hemorrhoid surgery with spinal-epidural anesthesia: A randomized trial
Manuscript Source Unsolicited Manuscript
All Author List Tao Hu, Qian Huang, Lai Wei, Shi Zhong and Jing Wang
ORCID
Author(s) ORCID Number
Tao Hu http://orcid.org/0009-0006-4263-8119
Qian Huang http://orcid.org/0009-0004-7147-2846
Shi Zhong http://orcid.org/0009-0007-9232-0341
Jing Wang http://orcid.org/0009-0004-2503-2671
Funding Agency and Grant Number
Funding Agency Grant Number
the Fundamental Research Funds for the Central Universities of Central South University 2024XQLH027
the Health Commission of Hunan Province 202204115263
Corresponding Author Jing Wang, MD, Department of Anesthesiology, The Second Xiangya Hospital, Central South University, No. 139 Renmin Middle Road, Changsha 410011, Hunan Province, China. 506858@csu.edu.cn
Key Words Procedure for prolapse and hemorrhoids surgery; Combined spinal-epidural anesthesia; Remimazolam-based combined anesthesia; State-Trait Anxiety Inventory-State Scale scores; Sedation depth; Hemodynamics
Core Tip In procedure for prolapse and hemorrhoids (PPH) surgery, traditional combined spinal-epidural (CSE) anesthesia commonly encounters challenges of insufficient intraoperative sedation and hemodynamic fluctuations. This study confirms that a remimazolam-based CSE anesthesia protocol significantly reduces patient anxiety before leaving the operating room and at 24 hours post-operation, while achieving deep sedation and stabilizing systolic blood pressure during critical surgical phases. The rapid onset of remimazolam's sedative effect and its anxiolytic properties offer an optimized approach to perioperative management of CSE anesthesia in PPH surgery.
Publish Date 2025-09-24 09:02
Citation <p>Hu T, Huang Q, Wei L, Zhong S, Wang J. Remimazolam reduces State-Trait Anxiety Inventory-State Scale scores in hemorrhoid surgery with spinal-epidural anesthesia: A randomized trial. <i>World J Gastrointest Surg</i> 2025; 17(9): 110034</p>
URL https://www.wjgnet.com/1948-9366/full/v17/i9/110034.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i9.110034
Full Article (PDF) WJGS-17-110034-with-cover.pdf
CONSORT 2010 Statement 110034-CONSORT-2010-statement.pdf
Manuscript File 110034_Auto_Edited_014024.docx
Answering Reviewers 110034-answering-reviewers.pdf
Audio Core Tip 110034-audio.mp3
Biostatistics Review Certificate 110034-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 110034-conflict-of-interest-statement.pdf
Copyright License Agreement 110034-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 110034-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 110034-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 110034-non-native-speakers.pdf
Peer-review Report 110034-peer-reviews.pdf
Scientific Misconduct Check 110034-scientific-misconduct-check.png
Scientific Editor Work List 110034-scientific-editor-work-list.pdf
CrossCheck Report 110034-crosscheck-report.pdf