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Articles Published Processes
10/25/2025 1:11:33 AM | Browse: 46 | Download: 11
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Received |
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2025-05-28 14:39 |
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Peer-Review Started |
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2025-05-28 14:39 |
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To Make the First Decision |
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Return for Revision |
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2025-06-27 02:04 |
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Revised |
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2025-07-10 15:38 |
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Second Decision |
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2025-09-01 00:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-02 07:45 |
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Articles in Press |
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2025-09-02 07:45 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-09-06 23:40 |
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Typeset the Manuscript |
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2025-10-15 07:31 |
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Publish the Manuscript Online |
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2025-10-25 01:11 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Review |
| Article Title |
Mesenchymal stem cell-derived microRNAs: The key immunomodulators to prevent ocular tissue degeneration
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sneha Nair and Gowri Priya Chidambaranathan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Gowri Priya Chidambaranathan, Associate Professor, PhD, Department of Immunology and Stem Cell Biology, Aravind Medical Research Foundation, No. 1 Anna Nagar, Madurai 625020, Tamil Nādu, India. gowri@aravind.org |
| Key Words |
Mesenchymal stem cells; MicroRNA; Extracellular vesicles; Ocular diseases; Exosomes |
| Core Tip |
Mesenchymal stem cells (MSCs) are emerging as potent therapeutic agents for ocular degeneration due to their regenerative and immunomodulatory properties. A key mechanism of their action is through extracellular vesicles, which deliver bioactive cargoes, particularly microRNAs (miRNAs), to target cells. This review highlights the role of MSC-derived miRNAs in modulating immune responses and promoting repair in ocular diseases such as corneal injury, dry eye, diabetic retinopathy, age-related macular degeneration, retinitis pigmentosa, and glaucoma. It also explores the potential of engineering extracellular vesicles enriched with specific MSC-derived miRNAs as innovative, cell-free therapeutic strategies. |
| Publish Date |
2025-10-25 01:11 |
| Citation |
<p>Nair S, Chidambaranathan GP. Mesenchymal stem cell-derived microRNAs: The key immunomodulators to prevent ocular tissue degeneration. <i>World J Stem Cells</i> 2025; 17(10): 110058</p> |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i10/110058.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i10.110058 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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