BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
10/25/2025 1:11:33 AM | Browse: 252 | Download: 283
 |
Received |
|
2025-05-28 14:39 |
|
Peer-Review Started |
|
2025-05-28 14:39 |
|
First Decision by Editorial Office Director |
|
2025-06-27 02:04 |
|
Return for Revision |
|
2025-06-27 02:04 |
|
Revised |
|
2025-07-10 15:38 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2025-09-01 00:36 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-09-02 07:45 |
|
Articles in Press |
|
2025-09-02 07:45 |
|
Edit the Manuscript by Language Editor |
|
2025-09-06 23:40 |
|
Typeset the Manuscript |
|
2025-10-15 07:31 |
|
Publish the Manuscript Online |
|
2025-10-25 01:11 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Review |
| Article Title |
Mesenchymal stem cell-derived microRNAs: The key immunomodulators to prevent ocular tissue degeneration
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Sneha Nair and Gowri Priya Chidambaranathan |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Gowri Priya Chidambaranathan, Associate Professor, PhD, Department of Immunology and Stem Cell Biology, Aravind Medical Research Foundation, No. 1 Anna Nagar, Madurai 625020, Tamil Nādu, India. gowri@aravind.org |
| Key Words |
Mesenchymal stem cells; MicroRNA; Extracellular vesicles; Ocular diseases; Exosomes |
| Core Tip |
Mesenchymal stem cells (MSCs) are emerging as potent therapeutic agents for ocular degeneration due to their regenerative and immunomodulatory properties. A key mechanism of their action is through extracellular vesicles, which deliver bioactive cargoes, particularly microRNAs (miRNAs), to target cells. This review highlights the role of MSC-derived miRNAs in modulating immune responses and promoting repair in ocular diseases such as corneal injury, dry eye, diabetic retinopathy, age-related macular degeneration, retinitis pigmentosa, and glaucoma. It also explores the potential of engineering extracellular vesicles enriched with specific MSC-derived miRNAs as innovative, cell-free therapeutic strategies. |
| Publish Date |
2025-10-25 01:11 |
| Citation |
Nair S, Chidambaranathan GP. Mesenchymal stem cell-derived microRNAs: The key immunomodulators to prevent ocular tissue degeneration. World J Stem Cells 2025; 17(10): 110058 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i10/110058.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i10.110058 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
