| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Early vs conventional initiation of adjuvant chemotherapy in advanced gastric cancer: A propensity-matched outcomes study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li Lin, Peng Zhang, Ya-Yue Wang, Yi-Fan Cai, Li-Bing Wen, Wei-Ping Chen, Yi-Fan Xiao, Zhi-Kun Li and Guo-Yan Liu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Xiamen Natural Science Foundation of China |
3502Z20227347 |
|
| Corresponding Author |
Guo-Yan Liu, MD, PhD, Professor, Department of Gastrointestinal Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, No. 209 Hubin South Road, Siming District, Xiamen 361102, Fujian Province, China. liuguoyan@xmu.edu.cn |
| Key Words |
Gastric cancer; Adjuvant chemotherapy; Postoperative timing; Survival rate; Propensity score; Recurrence pattern |
| Core Tip |
This study pioneers the evaluation of adjuvant chemotherapy initiated within 10-13 days postgastrectomy under enhanced recovery protocols. Early initiation shows comparable survival outcomes to conventional timing but requires tailored dosing to mitigate toxicity. These findings suggest that early chemotherapy is both feasible and safe when carefully managed, and they emphasize the importance of integrating surgical recovery with oncologic treatment, offering a paradigm shift in personalized gastric cancer management. |
| Publish Date |
2025-11-13 06:51 |
| Citation |
<p>Lin L, Zhang P, Wang YY, Cai YF, Wen LB, Chen WP, Xiao YF, Li ZK, Liu GY. Early vs conventional initiation of adjuvant chemotherapy in advanced gastric cancer: A propensity-matched outcomes study. <i>World J Gastroenterol</i> 2025; 31(42): 110069</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i42/110069.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i42.110069 |
