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10/15/2025 9:03:25 AM | Browse: 81 | Download: 189
Publication Name World Journal of Diabetes
Manuscript ID 110097
Country Italy
Received
2025-05-29 06:17
Peer-Review Started
2025-05-29 08:07
First Decision by Editorial Office Director
2025-06-10 05:12
Return for Revision
2025-06-10 05:12
Revised
2025-06-23 18:55
Publication Fee Transferred
Second Decision by Editor
2025-09-03 02:54
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-09-18 07:29
Articles in Press
2025-09-18 07:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-09 02:44
Publish the Manuscript Online
2025-10-15 09:03
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title MicroRNA 375 and diabetes: A key regulator of β cell function and a promising non-invasive biomarker
Manuscript Source Invited Manuscript
All Author List Marina Pierantoni, Marcello Dell'Aira, Silvia Grassilli, Federica Brugnoli and Valeria Bertagnolo
ORCID
Author(s) ORCID Number
Federica Brugnoli http://orcid.org/0000-0002-6934-9396
Funding Agency and Grant Number
Corresponding Author Federica Brugnoli, PhD, Researcher, Department of Translational Medicine, University of Ferrara, Via Fossato di Mortara 70, Ferrara 44121, Italy. bgf@unife.it
Key Words Pancreatic β cells; MicroRNA 375; Type 1 diabetes; Type 2 diabetes; Gestational diabetes mellitus
Core Tip Diabetes mellitus is strongly linked to microRNA 375 (miR-375), the most abundant miRNA in pancreatic β cells, where it plays an essential role in cell development and insulin production. MiR-375 is detectable in blood, making it a promising non-invasive biomarker, but the exact relationship between circulating miR-375 levels and both type 1 diabetes and type 2 diabetes remains unclear. This review provides a comprehensive overview of the current understanding of how miR-375 contributes to the onset and progression of diabetes mellitus and its potential use as a tool for the management of this complex pathology.
Publish Date 2025-10-15 09:03
Citation

Pierantoni M, Dell'Aira M, Grassilli S, Brugnoli F, Bertagnolo V. MicroRNA 375 and diabetes: A key regulator of β cell function and a promising non-invasive biomarker. World J Diabetes 2025; 16(10): 110097

URL https://www.wjgnet.com/1948-9358/full/v16/i10/110097.htm
DOI https://dx.doi.org/10.4239/wjd.v16.i10.110097
Full Article (PDF) WJD-16-110097-with-cover.pdf
Manuscript File 110097_Auto_Edited_095053.docx
Answering Reviewers 110097-answering-reviewers.pdf
Audio Core Tip 110097-audio.m4a
Conflict-of-Interest Disclosure Form 110097-conflict-of-interest-statement.pdf
Copyright License Agreement 110097-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 110097-non-native-speakers.pdf
Peer-review Report 110097-peer-reviews.pdf
Journal Editor-in-Chief Review Report 110097-journal-editor-in-chief.pdf
Scientific Misconduct Check 110097-scientific-misconduct-check.png
Scientific Editor Work List 110097-scientific-editor-work-list.pdf
CrossCheck Report 110097-crosscheck-report.pdf