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9/15/2025 8:38:05 AM | Browse: 261 | Download: 35
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 110110
Country Oman
Received
2025-05-30 05:22
Peer-Review Started
2025-05-30 05:22
To Make the First Decision
Return for Revision
2025-06-18 02:17
Revised
2025-07-02 18:46
Second Decision
2025-08-12 02:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-13 09:53
Articles in Press
2025-08-13 09:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-01 08:21
Publish the Manuscript Online
2025-09-15 08:38
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Virology
Manuscript Type Editorial
Article Title Missing link: Viral RNA signatures in circulating exosomes as early diagnostic biomarkers for gastrointestinal cancers
Manuscript Source Invited Manuscript
All Author List Mahmoud Darweesh and Saeed Mohammadi
ORCID
Author(s) ORCID Number
Saeed Mohammadi http://orcid.org/0000-0001-9895-8468
Funding Agency and Grant Number
Funding Agency Grant Number
Oman Ministry of Higher Education, Research, and Innovation No. BFP/RGP/HSS/24/015
Corresponding Author Saeed Mohammadi, Assistant Professor, PhD, Natural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mouz University of Nizwa Campus, Nizwa 616, Ad Dakhiliyah, Oman. s.mohammadi@unizwa.edu.om
Key Words Exosomes; Viral RNA; Liquid biopsy; Gastrointestinal cancer; Early detection; Epstein-Barr virus; Hepatitis B virus; Hepatitis C virus; Biomarkers; Noncoding RNA
Core Tip Early and accurate diagnostic markers are essential for managing gastrointestinal (GI) cancers, as their prognosis is linked to the stage of detection. This editorial emphasizes the potential of virus-enriched exosomes as a novel, non-invasive diagnostic tool for early detection and monitoring of GI cancers, particularly those associated with oncogenic viruses like Epstein-Barr virus and hepatitis B virus. The viral RNA signatures within these circulating exosomes serve as a crucial missing link, providing specific, and non-invasive biomarkers that can not only aid in distinguishing malignant from benign conditions but also offer insights into tumor progression and potential therapeutic targets.
Publish Date 2025-09-15 08:38
Citation <p>Darweesh M, Mohammadi S. Missing link: Viral RNA signatures in circulating exosomes as early diagnostic biomarkers for gastrointestinal cancers. <i>World J Gastrointest Oncol</i> 2025; 17(9): 110110</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i9/110110.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i9.110110
Full Article (PDF) WJGO-17-110110-with-cover.pdf
Manuscript File 110110_Auto_Edited_045454.docx
Answering Reviewers 110110-answering-reviewers.pdf
Audio Core Tip 110110-audio.m4a
Conflict-of-Interest Disclosure Form 110110-conflict-of-interest-statement.pdf
Copyright License Agreement 110110-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 110110-non-native-speakers.pdf
Peer-review Report 110110-peer-reviews.pdf
Scientific Misconduct Check 110110-scientific-misconduct-check.png
Scientific Editor Work List 110110-scientific-editor-work-list.pdf
CrossCheck Report 110110-crosscheck-report.pdf