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Articles Published Processes
8/7/2025 6:39:57 AM | Browse: 166 | Download: 626
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Received |
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2025-05-30 06:25 |
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Peer-Review Started |
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2025-05-30 06:25 |
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First Decision by Editorial Office Director |
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2025-06-04 03:43 |
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Return for Revision |
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2025-06-04 03:43 |
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Revised |
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2025-06-14 10:40 |
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Publication Fee Transferred |
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2025-06-16 10:16 |
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Second Decision by Editor |
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2025-07-18 02:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-18 05:11 |
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Articles in Press |
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2025-07-18 05:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-04 01:49 |
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Publish the Manuscript Online |
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2025-08-07 06:39 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Outcomes of 5-aminosalicylates withdrawal due to non-adherence in ulcerative colitis patients: A step toward evaluating intermittent therapy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ali Atay, Mucahit Ergul, Oguz Ozturk, Kadir C Acun, Yavuz Cagir, Muhammed B Durak and Ilhami Yuksel |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ilhami Yuksel, Professor, Department of Gastroenterology, Faculty of Medicine, Ankara Yildirim Beyazit University, İhsan Dogramaci Cad. Bilkent, Ankara 06800, Türkiye. yukselilhami@hotmail.com |
| Key Words |
Inflammatory bowel disease; Ulcerative colitis; 5-aminosalicylates; Treatment withdrawal; Relapse; Intermittent therapy |
| Core Tip |
In this study, 5-aminosalicylate (5-ASA) withdrawal was observed in 3.4% of patients with ulcerative colitis (UC). Almost half of them developed a relapse. The majority of patients who experienced relapse were treated with 5-ASA monotherapy, while one-fourth of them required corticosteroids. No patients required biological agents, hospitalization, or surgery. Based on our long-term real-world data, intermittent therapy may represent a potentially safe and feasible strategy in terms of relapse risk in patients with UC. Notably, in patients who have sustained long-term clinical remission, a treatment interruption of up to one year may be considered safe. |
| Publish Date |
2025-08-07 06:39 |
| Citation |
Atay A, Ergul M, Ozturk O, Acun KC, Cagir Y, Durak MB, Yuksel I. Outcomes of 5-aminosalicylates withdrawal due to non-adherence in ulcerative colitis patients: A step toward evaluating intermittent therapy. World J Gastroenterol 2025; 31(30): 110112 |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i30/110112.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i30.110112 |
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