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10/30/2025 7:07:08 AM | Browse: 7 | Download: 21
Publication Name World Journal of Clinical Cases
Manuscript ID 110123
Country United States
Received
2025-05-30 02:03
Peer-Review Started
2025-05-30 02:03
First Decision by Editorial Office Director
2025-06-06 03:42
Return for Revision
2025-06-06 03:42
Revised
2025-06-15 01:17
Publication Fee Transferred
Second Decision by Editor
2025-09-01 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-09-01 07:29
Articles in Press
2025-09-01 07:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-24 00:39
Publish the Manuscript Online
2025-10-30 07:07
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Minireviews
Article Title Role of anti-inflammatory agent colchicine in atherosclerotic cardiovascular disease
Manuscript Source Invited Manuscript
All Author List Kevan English and Christine Uwibambe
ORCID
Author(s) ORCID Number
Kevan English http://orcid.org/0009-0006-8893-5696
Funding Agency and Grant Number
Corresponding Author Kevan English, MD, Department of Internal Medicine, University of Nebraska Medical Center, S 42nd & Emile St, Omaha, NE 68198, United States. keenglish@unmc.edu
Key Words Colchicine; Coronary artery disease; Atherosclerosis; Inflammation; Myocardial infarction; C-reactive protein; Cardiovascular disease
Core Tip Inflammation is now recognized as an essential component of atherosclerosis, and the anti-inflammatory agent colchicine, through a variety of actions, suppresses this response. Results from a meta-analysis of several randomized controlled trials that evaluated colchicine’s efficacy on cardiovascular outcomes led to its recent approval by the United States Food and Drug Administration for the management and prevention of atherosclerotic cardiovascular disease. It has been shown to reduce the risk of recurrent major adverse cardiovascular events, and clinical data now supports its use for secondary prevention in patients with established coronary artery disease, presumably due to its anti-inflammatory properties.
Publish Date 2025-10-30 07:07
Citation

English K, Uwibambe C. Role of anti-inflammatory agent colchicine in atherosclerotic cardiovascular disease. World J Clin Cases 2025; 13(31): 110123

URL https://www.wjgnet.com/2307-8960/full/v13/i31/110123.htm
DOI https://dx.doi.org/10.12998/wjcc.v13.i31.110123
Full Article (PDF) WJCC-13-110123-with-cover.pdf
Manuscript File 110123_Auto_Edited_084515.docx
Answering Reviewers 110123-answering-reviewers.pdf
Audio Core Tip 110123-audio.m4a
Conflict-of-Interest Disclosure Form 110123-conflict-of-interest-statement.pdf
Copyright License Agreement 110123-copyright-assignment.pdf
Peer-review Report 110123-peer-reviews.pdf
Scientific Misconduct Check 110123-scientific-misconduct-check.png
Scientific Editor Work List 110123-scientific-editor-work-list.pdf
CrossCheck Report 110123-crosscheck-report.pdf