| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Radiofrequency ablation with or without capecitabine maintenance therapy for lung oligometastases from colorectal cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ke-Ning Li, Lei-Lei Ying, Nan Du, Ying Wang, Hao-Zhe Huang, Yao-Hui Wang, Li-Chao Xu, Qing Zhao, Ge Song, Yu-Bin Hu, Wen-Tao Li, Yan Yan, Chao Chen and Xin-Hong He |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82072034 |
|
| Corresponding Author |
Xin-Hong He, Department of Interventional Radiology, Fudan University Shanghai Cancer Center, No. 270 Dongan Road, Xuhui District, Shanghai 200032, China. xinhong.he@shca.org.cn |
| Key Words |
Colorectal cancer; Lung oligometastases; Radiofrequency ablation; Capecitabine; Maintenance therapy |
| Core Tip |
This multicenter retrospective analysis demonstrates that adding maintenance capecitabine after achieving no evidence of disease with radiofrequency ablation (RFA) significantly improves survival outcomes in colorectal cancer patients with lung oligometastases. Compared to RFA alone, the RFA-plus-capecitabine group showed superior 5-year overall survival and significantly reduced local tumor progression, although progression-free survival was unchanged. This study provides the first evidence supporting capecitabine maintenance therapy following RFA-induced no evidence of disease as a strategy to enhance long-term survival and local control in this oligometastatic population. |
| Publish Date |
2025-09-18 09:55 |
| Citation |
<p>Li KN, Ying LL, Du N, Wang Y, Huang HZ, Wang YH, Xu LC, Zhao Q, Song G, Hu YB, Li WT, Yan Y, Chen C, He XH. Radiofrequency ablation with or without capecitabine maintenance therapy for lung oligometastases from colorectal cancer. <i>World J Gastroenterol</i> 2025; 31(35): 110152</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i35/110152.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i35.110152 |
