Publication Name	World Journal of Gastroenterology
Manuscript ID	110210
Country	Saudi Arabia

Received	2025-06-04 04:35
Peer-Review Started	2025-06-04 04:39
To Make the First Decision
Return for Revision	2025-06-17 10:44
Revised	2025-06-30 08:08
Second Decision	2025-08-27 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-27 06:59
Articles in Press	2025-08-27 06:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-09-11 06:47
Publish the Manuscript Online	2025-09-19 07:57

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Colonic neoplasia and celiac disease: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Yasir M Khayyat
ORCID	Author(s) ORCID Number Yasir M Khayyat http://orcid.org/0000-0002-8344-2028
Funding Agency and Grant Number
Corresponding Author	Yasir M Khayyat, FACG, FACP, FRCP (C), Professor, Department of Medicine, Faculty of Medicine, Umm AL-Qura University, AlAwali District, Makkah 8156-24381, Saudi Arabia. ymkhayyat@uqu.edu.sa
Key Words	Celiac disease; Gluten; Colon; Lymphoma; Cancer
Core Tip	Celiac disease (CD) involves proinflammatory mechanisms that predispose untreated patients who adhere to a gluten-free diet to the development of neoplastic complications. Gluten peptides have known direct effects on several levels of cell structure, and they increase proinflammatory potential and oncogenesis. Neoplastic complications of the colorectum are considered rare among neoplasms induced by CD. Intestinal lymphoma is a recognized and well-known long-term complication of CD; however, little is known about its role in colorectal cancer. The unfavorable outcomes related to colorectal lymphoma and adenocarcinoma associated with CD require further evaluation to inform possible screening initiatives.
Publish Date	2025-09-19 07:57
Citation	<p>Khayyat YM. Colonic neoplasia and celiac disease: A systematic review. <i>World J Gastroenterol</i> 2025; 31(36): 110210</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i36/110210.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i36.110210

Full Article (PDF)	WJG-31-110210-with-cover.pdf
PRISMA 2009 Checklist	110210-PRISMA-2009-Checklist.pdf
Manuscript File	110210_Auto_Edited_031742.docx
Answering Reviewers	110210-answering-reviewers.pdf
Audio Core Tip	110210-audio.m4a
Biostatistics Review Certificate	110210-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	110210-conflict-of-interest-statement.pdf
Copyright License Agreement	110210-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	110210-non-native-speakers.pdf
Peer-review Report	110210-peer-reviews.pdf
Scientific Misconduct Check	110210-scientific-misconduct-check.png
Scientific Editor Work List	110210-scientific-editor-work-list.pdf
CrossCheck Report	110210-crosscheck-report.pdf