| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Observational Study |
| Article Title |
Association between uric acid to high-density lipoprotein ratio and mental health symptoms in people with type 2 diabetes
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Hui Xu, Dong-Juan He, Cheng Luo, Xian-Mei Yu, Cheng-Zheng Duan, Da Sun, De-Jun Wu, Xiao-Qiang Mao and Wei-Feng Jiang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Program of Quzhou, China |
2022K67 |
| Zhejiang Medical Association Clinical Research Fund Project |
2024ZYC-A526 |
| Research Project of Quzhou People's Hospital |
KYQD2024-006 |
|
| Corresponding Author |
Wei-Feng Jiang, Associate Chief Physician, MD, Department of Gerontology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, No. 100 Minjiang Avenue, Kecheng District, Quzhou 324000, Zhejiang Province, China. weifengjiang@wmu.edu.cn |
| Key Words |
Anxiety; Depression; Type 2 diabetes mellitus; Uric acid; High-density lipoprotein cholesterol; Uric acid to high-density lipoprotein cholesterol ratio |
| Core Tip |
This study highlights the significant association between the uric acid to high-density lipoprotein cholesterol ratio (UHR) and symptoms of depression and anxiety in individuals with type 2 diabetes mellitus (T2DM). Using multivariate and nonlinear analyses, the study identifies threshold effects, suggesting that elevated UHR levels may serve as a cost-effective biomarker for psychological distress in T2DM. These findings underscore the importance of integrating metabolic and mental health assessments in diabetic care, particularly in high-risk subgroups. |
| Publish Date |
2025-10-15 09:03 |
| Citation |
<p>Xu H, He DJ, Luo C, Yu XM, Duan CZ, Sun D, Wu DJ, Mao XQ, Jiang WF. Association between uric acid to high-density lipoprotein ratio and mental health symptoms in people with type 2 diabetes. <i>World J Diabetes</i> 2025; 16(10): 110211</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i10/110211.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i10.110211 |
