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12/31/2025 5:47:40 AM | Browse: 2 | Download: 1
Publication Name World Journal of Psychiatry
Manuscript ID 110298
Country China
Received
2025-08-08 08:37
Peer-Review Started
2025-08-08 08:37
First Decision by Editorial Office Director
2025-09-02 02:05
Return for Revision
2025-09-02 02:05
Revised
2025-09-23 12:56
Publication Fee Transferred
Second Decision by Editor
2025-10-30 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-30 07:07
Articles in Press
2025-10-30 07:07
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-19 01:56
Publish the Manuscript Online
2025-12-31 05:47
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychology
Manuscript Type Retrospective Study
Article Title Effects of celecoxib combined with duloxetine on chronic pain, depression, and anxiety in patients with knee osteoarthritis
Manuscript Source Unsolicited Manuscript
All Author List Xin Liu, Qing Fang, Yin-Di Sun, Na Liu, Hao-Hao Liang and Liang Li
ORCID
Author(s) ORCID Number
Hao-Hao Liang http://orcid.org/0009-0001-9465-0834
Liang Li http://orcid.org/0009-0005-7881-3081
Funding Agency and Grant Number
Corresponding Author Liang Li, Pain ward of Orthopedics of Traditional Chinese Medicine, Honghui Hospital, Xi'an Jiaotong University, Xi’an 710000, Shaanxi Province, China. ll2271005@163.com
Key Words Knee osteoarthritis; Chronic pain; Anxiety; Depression; Celecoxib; Duloxetine
Core Tip This study provides an in-depth evaluation of the effects of celecoxib combined with duloxetine on chronic pain, anxiety, and depression in patients with knee osteoarthritis (KOA). The findings indicate that the combined regimen is more effective than monotherapy in reducing pain, improving knee function, and alleviating anxiety and depression.Furthermore, patient age, educational background, and treatment regimen were identified as independent factors influencing emotional outcomes, offering practical guidance for individualized treatment planning. These findings highlight the potential of this therapeutic approach to improve overall clinical outcomes and quality of life in patients with KOA.
Publish Date 2025-12-31 05:47
Citation

Liu X, Fang Q, Sun YD, Liu N, Liang HH, Li L. Effects of celecoxib combined with duloxetine on chronic pain, depression, and anxiety in patients with knee osteoarthritis. World J Psychiatry 2026; 16(1): 110298

URL https://www.wjgnet.com/2220-3206/full/v16/i1/110298.htm
DOI https://dx.doi.org/10.5498/wjp.v16.i1.110298
Full Article (PDF) WJP-16-110298-with-cover.pdf
Manuscript File 110298_Auto_Edited_010452.docx
Answering Reviewers 110298-answering-reviewers.pdf
Audio Core Tip 110298-audio.mp3
Biostatistics Review Certificate 110298-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 110298-conflict-of-interest-statement.pdf
Copyright License Agreement 110298-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 110298-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 110298-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 110298-non-native-speakers.pdf
Peer-review Report 110298-peer-reviews.pdf
Scientific Misconduct Check 110298-scientific-misconduct-check.png
Scientific Editor Work List 110298-scientific-editor-work-list.pdf
CrossCheck Report 110298-crosscheck-report.pdf