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12/26/2025 10:27:30 AM | Browse: 1 | Download: 1
Publication Name World Journal of Hepatology
Manuscript ID 110303
Country Russia
Received
2025-06-04 03:47
Peer-Review Started
2025-06-04 03:48
First Decision by Editorial Office Director
2025-07-08 09:24
Return for Revision
2025-07-08 09:24
Revised
2025-07-16 09:07
Publication Fee Transferred
Second Decision by Editor
2025-11-11 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-12 05:39
Articles in Press
2025-11-12 05:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-18 01:11
Publish the Manuscript Online
2025-12-26 10:27
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Clinical and biological significance of the relationship between gut microbiota and liver disease
Manuscript Source Invited Manuscript
All Author List Stanislav N Kotlyarov
ORCID
Author(s) ORCID Number
Stanislav N Kotlyarov http://orcid.org/0000-0002-7083-2692
Funding Agency and Grant Number
Corresponding Author Stanislav N Kotlyarov, PhD, Professor, Department of Nurse, Ryazan State Medical University, Russian Federation, Ryazan, Vysokovoltnaya, 9, Ryazan 390005, Russia. skmr1@yandex.ru
Key Words Gut microbiota; Liver disease; Immunometabolism; Nonalcoholic fatty liver disease; Bile; Innate immune system; Short-chain fatty acids
Core Tip The gut microbiota has numerous metabolic and immune connections not only to the gut itself but also to other organs, including the lungs, brain, and liver. The gut–liver connection is bidirectional, and disruptions in this relationship contribute to the development of various liver diseases. Modulation of gut microbiota composition and function forms the basis of therapeutic strategies for conditions such as non-alcoholic fatty liver disease, cirrhosis, and hepatocellular carcinoma.
Publish Date 2025-12-26 10:27
Citation

Kotlyarov SN. Clinical and biological significance of the relationship between gut microbiota and liver disease. World J Hepatol 2025; 17(12): 110303

URL https://www.wjgnet.com/1948-5182/full/v17/i12/110303.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i12.110303
Full Article (PDF) WJH-17-110303-with-cover.pdf
Manuscript File 110303_Auto_Edited_025402.docx
Answering Reviewers 110303-answering-reviewers.pdf
Audio Core Tip 110303-audio.mp3
Conflict-of-Interest Disclosure Form 110303-conflict-of-interest-statement.pdf
Copyright License Agreement 110303-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 110303-non-native-speakers.pdf
Supplementary Material 110303-supplementary-material.pdf
Peer-review Report 110303-peer-reviews.pdf
Scientific Misconduct Check 110303-scientific-misconduct-check.png
Scientific Editor Work List 110303-scientific-editor-work-list.pdf
CrossCheck Report 110303-crosscheck-report.pdf