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Articles Published Processes
11/19/2025 5:57:50 AM | Browse: 16 | Download: 15
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Received |
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2025-06-04 03:51 |
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Peer-Review Started |
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2025-06-04 03:51 |
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To Make the First Decision |
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Return for Revision |
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2025-06-07 02:23 |
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Revised |
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2025-06-08 15:25 |
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Second Decision |
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2025-08-01 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-01 11:58 |
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Articles in Press |
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2025-08-01 11:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-21 06:19 |
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Publish the Manuscript Online |
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2025-11-19 05:57 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Interpreting the hazard zone: Factor V and lactate as critical indicators in severe early allograft injury
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Marco Zeppieri, Giovanni Miotti and Martina Grando |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Marco Zeppieri, MD, PhD, Department of Ophthalmology, University Hospital of Udine, p. le S. Maria della Misericordia 15, Udine 33100, Italy. mark.zeppieri@asufc.sanita.fvg.it |
| Key Words |
Liver transplantation; Early allograft failure; Factor V; Arterial lactate; Biomarker-guided decision-making |
| Core Tip |
In liver transplant recipients, quick identification of grafts susceptible to failure continues to be a clinical challenge, especially when aminotransferase levels exceed 5000 U/L during the early postoperative phase. Although generally considered concerning, these increases do not always indicate poor prognosis. For this reason, the use of functional biomarkers, such as serum factor V and arterial lactate levels, is highly considered to more accurately distinguish patients with a greater chance of recovery from those at risk of early transplant failure. Incorporating these elements into daily clinical practice can improve decision making, minimize retransplantations, optimizing patient outcomes and organ preservation. |
| Publish Date |
2025-11-19 05:57 |
| Citation |
<p>Zeppieri M, Miotti G, Grando M. Interpreting the hazard zone: Factor V and lactate as critical indicators in severe early allograft injury. <i>World J Transplant</i> 2025; 15(4): 110310</p> |
| URL |
https://www.wjgnet.com/2220-3230/full/v15/i4/110310.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v15.i4.110310 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
