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12/26/2025 10:27:33 AM | Browse: 1 | Download: 1
Publication Name World Journal of Hepatology
Manuscript ID 110312
Country Chile
Received
2025-06-12 08:39
Peer-Review Started
2025-06-12 08:39
First Decision by Editorial Office Director
2025-06-18 07:11
Return for Revision
2025-06-18 07:11
Revised
2025-07-01 17:10
Publication Fee Transferred
2025-10-29 12:43
Second Decision by Editor
2025-11-17 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-17 08:54
Articles in Press
2025-11-17 08:54
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-18 02:14
Publish the Manuscript Online
2025-12-26 10:27
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Impact of age on autoimmune hepatitis: A comparative study of patients diagnosed before and after sixty
Manuscript Source Unsolicited Manuscript
All Author List Javier Delgado, Marcelo Fuentes, Daniela Simian, Jaime Poniachik and Álvaro Urzúa
ORCID
Author(s) ORCID Number
Daniela Simian http://orcid.org/0000-0002-5309-1503
Jaime Poniachik http://orcid.org/0000-0001-7958-3357
Álvaro Urzúa http://orcid.org/0000-0002-8059-8844
Funding Agency and Grant Number
Corresponding Author Álvaro Urzúa, MD, Division of Gastroenterology, Department of Medicine, Hospital Clínico Universidad de Chile, Dr. Carlos Lorca Tobar 999, Independencia, Santiago 8380456, Región Metropolitana, Chile. aurzuam@hcuch.cl
Key Words Autoimmune hepatitis; Elderly; Diagnosis; Steroids; Fibrosis
Core Tip This study highlights age-related differences in autoimmune hepatitis (AIH) presentation. Patients diagnosed after 60 years of age showed milder biochemical abnormalities but more advanced fibrosis and ascites at diagnosis. Despite receiving lower corticosteroid doses, their treatment response was comparable to younger patients. These findings suggest that AIH in older adults may represent a distinct clinical phenotype with important diagnostic and therapeutic implications.
Publish Date 2025-12-26 10:27
Citation

Delgado J, Fuentes M, Simian D, Poniachik J, Urzúa Á. Impact of age on autoimmune hepatitis: A comparative study of patients diagnosed before and after sixty. World J Hepatol 2025; 17(12): 110312

URL https://www.wjgnet.com/1948-5182/full/v17/i12/110312.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i12.110312
Full Article (PDF) WJH-17-110312-with-cover.pdf
STROBE Statement 110312-STROBE-statement.pdf
Manuscript File 110312_Auto_Edited_065545.docx
Answering Reviewers 110312-answering-reviewers.pdf
Audio Core Tip 110312-audio.mp3
Biostatistics Review Certificate 110312-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 110312-conflict-of-interest-statement.pdf
Copyright License Agreement 110312-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 110312-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 110312-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 110312-non-native-speakers.pdf
Peer-review Report 110312-peer-reviews.pdf
Scientific Misconduct Check 110312-scientific-misconduct-check.png
Scientific Editor Work List 110312-scientific-editor-work-list.pdf
CrossCheck Report 110312-crosscheck-report.pdf