BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
11/25/2025 11:05:31 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 110323
Country China
Received
2025-06-04 04:14
Peer-Review Started
2025-06-04 04:14
To Make the First Decision
Return for Revision
2025-06-20 02:25
Revised
2025-07-19 03:41
Second Decision
2025-09-09 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-09 07:17
Articles in Press
2025-09-09 07:17
Publication Fee Transferred
2025-07-23 13:52
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-17 04:18
Publish the Manuscript Online
2025-11-25 11:05
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Advancements in injection materials for submucosal lifting in endoscopic interventions
Manuscript Source Unsolicited Manuscript
All Author List Peng-Wei Xu, Zheng-Han Xiao, Miao Yu and Xue-Yan Zhang
ORCID
Author(s) ORCID Number
Peng-Wei Xu http://orcid.org/0009-0007-1645-5666
Xue-Yan Zhang http://orcid.org/0000-0001-5879-4446
Funding Agency and Grant Number
Corresponding Author Xue-Yan Zhang, PhD, Professor, Department of Gastroenterology, The Second Affiliated Hospital of Harbin Medical University, No. 246 Xuefu Road, Nangang District, Harbin 150086, Heilongjiang Province, China. zxycxw@sina.com
Key Words Submucosal injection material; Submucosal fluid cushion; Endoscopic submucosal dissection; Endoscopic mucosal resection; Clinical translation challenges
Core Tip Submucosal injection cushions are essential adjuncts for achieving safe and effective endoscopic resection. Despite advances in material design - aimed at enhancing lift durability and incorporating biofunctional properties - their clinical translation remains constrained. Key limiting factors include suboptimal injectability, insufficient long-term biocompatibility data, restricted functional versatility, and substantial hurdles in manufacturing scalability, regulatory approval, and reimbursement. This article provides a critical comparison of conventional and next-generation submucosal injection materials, delineates major translational bottlenecks, and proposes integrative strategies to support their clinical implementation.
Publish Date 2025-11-25 11:05
Citation <p>Xu PW, Xiao ZH, Yu M, Zhang XY. Advancements in injection materials for submucosal lifting in endoscopic interventions. <i>World J Gastrointest Surg</i> 2025; 17(11): 110323</p>
URL https://www.wjgnet.com/1948-9366/full/v17/i11/110323.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i11.110323
Full Article (PDF) WJGS-17-110323-with-cover.pdf
Manuscript File 110323_Auto_Edited_015201.docx
Answering Reviewers 110323-answering-reviewers.pdf
Audio Core Tip 110323-audio.mp3
Conflict-of-Interest Disclosure Form 110323-conflict-of-interest-statement.pdf
Copyright License Agreement 110323-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 110323-non-native-speakers.pdf
Peer-review Report 110323-peer-reviews.pdf
Scientific Misconduct Check 110323-scientific-misconduct-check.png
Scientific Editor Work List 110323-scientific-editor-work-list.pdf
CrossCheck Report 110323-crosscheck-report.pdf