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Articles Published Processes
9/18/2025 9:55:58 AM | Browse: 351 | Download: 71
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Received |
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2025-06-06 17:00 |
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Peer-Review Started |
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2025-06-06 17:00 |
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To Make the First Decision |
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Return for Revision |
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2025-06-11 07:43 |
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Revised |
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2025-06-24 19:22 |
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Second Decision |
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2025-08-20 02:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-20 08:36 |
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Articles in Press |
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2025-08-20 08:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-08 07:24 |
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Publish the Manuscript Online |
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2025-09-18 09:55 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
From bench to bedside: Advancements in patient-derived xenografts for predicting therapy outcomes in colorectal cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Andrei Nicolae Ceobanu, Alexandru Florin Braniște, Ştefan Morărașu and Gabriel Mihail Dimofte |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| European Union, the Romanian Government and the Health Program (Medical Applications of High-Power Lasers - Dr. LASER) |
MySMIS2021/SMIS2021+ 326475 |
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| Corresponding Author |
Alexandru Florin Braniște, MD, Department of Endocrinology, University of Medicine and Pharmacy “Grigore T Popa”, Emergency Clinical County Hospital “Saint Spiridon”, 16 University Street, Iasi 700115, Romania. alexandru-florin.braniste@d.umfiasi.ro |
| Key Words |
Zebrafish; Mouse; Patient-derived xenografts; Colorectal cancer; Translational medicine |
| Core Tip |
This minireview discussed the use of patient-derived xenograft (PDX) models in mice and zebrafish and their impact on predicting treatment outcomes in patients with colorectal cancer. Each model has its own unique advantages and disadvantages that are useful in certain situations. Mouse PDX models are better suited for longer-term and in-depth studies, and zebrafish PDX models are better for chemoprofiling and short-term treatment guidance. We also discussed the applicability of these models for personalized medicine and the synergy with current biomarkers to better select treatment. |
| Publish Date |
2025-09-18 09:55 |
| Citation |
<p>Ceobanu AN, Braniște AF, Morărașu Ş, Dimofte GM. From bench to bedside: Advancements in patient-derived xenografts for predicting therapy outcomes in colorectal cancer. <i>World J Gastroenterol</i> 2025; 31(35): 110370</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i35/110370.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i35.110370 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
