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Articles Published Processes
2/11/2015 4:38:00 PM | Browse: 1178 | Download: 1516
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Received |
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2014-05-01 09:36 |
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Peer-Review Started |
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2014-05-02 12:16 |
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To Make the First Decision |
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2014-05-29 19:01 |
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Return for Revision |
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2014-06-05 12:02 |
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Revised |
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2014-08-01 17:56 |
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Second Decision |
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2014-09-16 13:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-09-16 13:48 |
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Articles in Press |
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2014-09-16 13:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-02-04 14:38 |
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Publish the Manuscript Online |
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2015-02-11 16:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Autobiography |
| Article Title |
Depletion of the IKBKAP ortholog in zebrafish leads to hirschsprung disease-like phenotype
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| Manuscript Source |
Invited Manuscript |
| All Author List |
William Wai-Chun Cheng, Clara Sze-Man Tang, Hong-Sheng Gui, Man-Ting So, Vincent Chi-Hang Lui, Paul Kwong-Hang Tam and Maria-Mercè Garcia-Barcelo |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the University of Hong Kong |
201209176125 to Cheng WWC |
| Hong Kong Research Grants Council HKU |
78610M to Tam PKH |
| Health and Medical Research Fund |
01121326 to Lui VCH |
| University of Hong Kong Genomics Strategic Research Theme |
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| Corresponding Author |
Maria-Mercè Garcia-Barcelo, Associate Professor, Department of Surgery, Li Ka Shing Faculty of Medicine, the University of Hong Kong, 9/F Faculty of Medicine Building, 21 Sassoon Road, Pokfulam,
Hong Kong, China. mmgarcia@hku.hk
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| Key Words |
Hirschsprung disease; Enteric nervous system; IKBKAP; Zebrafish; Morpholinos |
| Core Tip |
To investigate the functional role of IKBKAP in enteric nervous system (ENS) development, we knocked down the zebrafish ortholog ikbkap using a translation blocking antisense morpholino. Loss of ikbkap caused aganglionosis and a reduced number of enteric neurons, indicating that IKBKAP is important for proper ENS development. |
| Publish Date |
2015-02-11 16:38 |
| Citation |
Cheng WWC, Tang CSM, Gui HS, So MT, Lui VCH, Tam PKH, Garcia-Barcelo MM. Depletion of the IKBKAP ortholog in zebrafish leads to hirschsprung disease-like phenotype. World J Gastroenterol 2015; 21(7): 2040-2046 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i7/2040.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i7.2040 |
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