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2/11/2015 4:38:00 PM | Browse: 941 | Download: 1065
Publication Name World Journal of Gastroenterology
Manuscript ID 11040
Country China
Received
2014-05-01 09:36
Peer-Review Started
2014-05-02 12:16
To Make the First Decision
2014-05-29 19:01
Return for Revision
2014-06-05 12:02
Revised
2014-08-01 17:56
Second Decision
2014-09-16 13:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-09-16 13:48
Articles in Press
2014-09-16 13:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-02-04 14:38
Publish the Manuscript Online
2015-02-11 16:38
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Autobiography
Article Title Depletion of the IKBKAP ortholog in zebrafish leads to hirschsprung disease-like phenotype
Manuscript Source Invited Manuscript
All Author List William Wai-Chun Cheng, Clara Sze-Man Tang, Hong-Sheng Gui, Man-Ting So, Vincent Chi-Hang Lui, Paul Kwong-Hang Tam and Maria-Mercè Garcia-Barcelo
Funding Agency and Grant Number
Funding Agency Grant Number
the University of Hong Kong 201209176125 to Cheng WWC
Hong Kong Research Grants Council HKU 78610M to Tam PKH
Health and Medical Research Fund 01121326 to Lui VCH
University of Hong Kong Genomics Strategic Research Theme
Corresponding Author Maria-Mercè Garcia-Barcelo, Associate Professor, Department of Surgery, Li Ka Shing Faculty of Medicine, the University of Hong Kong, 9/F Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong, China. mmgarcia@hku.hk
Key Words Hirschsprung disease; Enteric nervous system; IKBKAP; Zebrafish; Morpholinos
Core Tip To investigate the functional role of IKBKAP in enteric nervous system (ENS) development, we knocked down the zebrafish ortholog ikbkap using a translation blocking antisense morpholino. Loss of ikbkap caused aganglionosis and a reduced number of enteric neurons, indicating that IKBKAP is important for proper ENS development.
Publish Date 2015-02-11 16:38
Citation Cheng WWC, Tang CSM, Gui HS, So MT, Lui VCH, Tam PKH, Garcia-Barcelo MM. Depletion of the IKBKAP ortholog in zebrafish leads to hirschsprung disease-like phenotype. World J Gastroenterol 2015; 21(7): 2040-2046
URL http://www.wjgnet.com/1007-9327/full/v21/i7/2040.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i7.2040
Full Article (PDF) WJG-21-2040.pdf
Full Article (Word) WJG-21-2040.doc
Manuscript File 11040-Review.docx
Answering Reviewers 11040-Answering reviewers.pdf
Copyright License Agreement 11040-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 11040-Language certificate.pdf
Peer-review Report 11040-Peer reviews.pdf
Scientific Misconduct Check 11040-CrossCheck.jpg
Scientific Editor Work List 11040-Scientific editor work list.pdf