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12/23/2025 8:03:22 AM | Browse: 13 | Download: 44
Publication Name World Journal of Nephrology
Manuscript ID 110414
Country India
Received
2025-06-09 09:28
Peer-Review Started
2025-06-09 09:29
First Decision by Editorial Office Director
2025-07-02 02:54
Return for Revision
2025-07-02 02:54
Revised
2025-07-15 18:27
Publication Fee Transferred
Second Decision by Editor
2025-10-23 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-24 04:24
Articles in Press
2025-10-24 04:24
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-16 00:19
Publish the Manuscript Online
2025-12-23 08:03
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Minireviews
Article Title Acute kidney injury associated with acute fatty liver of pregnancy: An update on a rare clinical entity
Manuscript Source Invited Manuscript
All Author List Meenakshi Rajput, Sumitra Bachani, Jyotsna Suri, Rekha Bharti, Adarsh Kumar, Rajesh Kumar, Himanshu Verma and Pallavi Prasad
ORCID
Author(s) ORCID Number
Meenakshi Rajput http://orcid.org/0009-0007-0077-3715
Adarsh Kumar http://orcid.org/0000-0001-5842-1324
Funding Agency and Grant Number
Corresponding Author Adarsh Kumar, Department of Nephrology and Renal Transplant Medicine, Vardhman Mahavir Medical College (VMMC) and Safdarjung Hospital, Ansari Nagar East, Near AIIMS Metro Station, New Delhi 110029, Delhi, India. adarshnephro081@gmail.com
Key Words Acute kidney injury; Acute tubular necrosis; Acute fatty liver of pregnancy; Pregnancy complications; Therapeutic plasma exchange
Core Tip Acute kidney injury (AKI) associated with acute fatty liver of pregnancy (AFLP) occurs more frequently than AKI related to preeclampsia or hemolysis, elevated liver enzymes, and low platelets syndrome; however, it is generally non-oliguric and of relatively low severity. In some cases, kidney function may not fully recover after delivery and could require dialysis. Rarely, AFLP can manifest in the postpartum period, which presents a diagnostic challenge due to lack of prodromal symptoms and occurrence of severe AKI. AKI is key characteristic of AFLP and is included in both its diagnostic and prognostic criteria. Therapeutic plasma exchange may be considered in patients with persistent hepatic or renal dysfunction following delivery. Given that rapid recognition and prompt delivery are crucial for managing AFLP, there is a need for biomarkers, similar to the soluble fms-like tyrosine kinase-1/placental growth factor ratio used in preeclampsia, that can facilitate earlier diagnosis and treatment.
Publish Date 2025-12-23 08:03
Citation

Rajput M, Bachani S, Suri J, Bharti R, Kumar A, Kumar R, Verma H, Prasad P. Acute kidney injury associated with acute fatty liver of pregnancy: An update on a rare clinical entity. World J Nephrol 2025; 14(4): 110414

URL https://www.wjgnet.com/2220-6124/full/v14/i4/110414.htm
DOI https://dx.doi.org/10.5527/wjn.v14.i4.110414
Full Article (PDF) WJN-14-110414-with-cover.pdf
Manuscript File 110414_Auto_Edited_020256.docx
Answering Reviewers 110414-answering-reviewers.pdf
Audio Core Tip 110414-audio.m4a
Conflict-of-Interest Disclosure Form 110414-conflict-of-interest-statement.pdf
Copyright License Agreement 110414-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 110414-non-native-speakers.pdf
Peer-review Report 110414-peer-reviews.pdf
Scientific Misconduct Check 110414-scientific-misconduct-check.png
Scientific Editor Work List 110414-scientific-editor-work-list.pdf
CrossCheck Report 110414-crosscheck-report.pdf