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Articles Published Processes
11/14/2025 7:35:09 AM | Browse: 9 | Download: 68
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Received |
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2025-06-07 03:45 |
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Peer-Review Started |
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2025-06-07 03:45 |
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To Make the First Decision |
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Return for Revision |
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2025-07-02 02:52 |
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Revised |
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2025-07-05 03:09 |
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Second Decision |
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2025-09-28 02:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-28 08:44 |
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Articles in Press |
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2025-09-28 08:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-16 06:25 |
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Publish the Manuscript Online |
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2025-11-14 07:35 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Observational Study |
| Article Title |
Osteoporosis and fragility fractures in patients with acromegaly: A two-center cross-sectional study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mauricio Alvarez, Juliana Rincon, Maria Mercedes Ulloa, Oswaldo Rincon, Liliana Mejia, Alejandra Alvarado, Andres Pereira and Mónica Bernal |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mauricio Alvarez, Associate Professor, MD, Department of Endocrinology, Hospital Militar Central, Tv. 3C No. 49-02, Bogota 110221, Distrito Capital de Bogotá, Colombia. mauricioalvarez613@gmail.com |
| Key Words |
Acromegaly; Bone density; Spinal fractures; Osteoporosis; Pituitary gland; Growth hormone-secreting pituitary adenoma |
| Core Tip |
The current study found a high prevalence of osteoporosis and non-vertebral fragility fractures in patients with acromegaly, independent of age, sex, body mass index, time from diagnosis, insulin-like growth factor level, and disease control and regardless of the presence of independent risk factors. Somatostatin analog therapy in patients with acromegaly was associated with a higher risk for having osteoporosis. Taken together, our results suggest that the severity of the disease and the need for second-line therapies, rather than a specific medication for acromegaly, may be associated with the increased risk of osteoporosis. However, further studies are required to assess the effect of somatostatin analogs on bone metabolism. |
| Publish Date |
2025-11-14 07:35 |
| Citation |
<p>Alvarez M, Rincon J, Ulloa MM, Rincon O, Mejia L, Alvarado A, Pereira A, Bernal M. Osteoporosis and fragility fractures in patients with acromegaly: A two-center cross-sectional study. <i>World J Orthop</i> 2025; 16(11): 110420</p> |
| URL |
https://www.wjgnet.com/2218-5836/full/v16/i11/110420.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v16.i11.110420 |
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