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Articles Published Processes
12/22/2025 7:43:02 AM | Browse: 0 | Download: 0
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Received |
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2025-06-07 02:58 |
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Peer-Review Started |
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2025-06-07 02:58 |
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First Decision by Editorial Office Director |
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2025-06-24 11:00 |
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Return for Revision |
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2025-06-24 11:00 |
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Revised |
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2025-07-04 17:31 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-04 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-04 06:13 |
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Articles in Press |
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2025-11-04 06:13 |
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Edit the Manuscript by Language Editor |
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2025-11-09 02:26 |
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Typeset the Manuscript |
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2025-12-10 07:58 |
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Publish the Manuscript Online |
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2025-12-22 07:43 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Delayed orocecal transit in pediatric gut-brain interaction disorders: A comparative study using the lactulose breath test
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Niranga Manjuri Devanarayana, Shaman Rajindrajith, Delpechitracharige Gajabahu Harendra de Silva and Hithanadura Janaka de Silva |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| University of Kelaniya |
RP/03/04/13/01/01 |
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| Corresponding Author |
Niranga Manjuri Devanarayana, MD, PhD, Professor, Department of Physiology, Faculty of Medicine, University of Kelaniya, Thalagolla Road, Ragama 11010, Western Province, Sri Lanka. niranga@kln.ac.lk |
| Key Words |
Abdominal pain; Child; Disorders of gut-brain interaction; Functional gastrointestinal disorders; Gastrointestinal transit; Lactulose breath test |
| Core Tip |
This study evaluated orocecal transit time (OCTT) using the breath hydrogen test in children with functional abdominal pain disorders (FAPDs). Results showed significantly longer OCTT in patients compared to healthy controls, suggesting that impaired small intestinal transit may be a feature of FAPDs. However, the absence of correlation between OCTT and symptom severity indicates that delayed transit is unlikely to be a major contributor to symptom generation. These findings highlight the complexity of FAPD pathophysiology and suggest that while small intestinal motility disturbances are present, other mechanisms likely play a key role in symptom expression. |
| Publish Date |
2025-12-22 07:43 |
| Citation |
Devanarayana NM, Rajindrajith S, de Silva DGH, de Silva HJ. Delayed orocecal transit in pediatric gut-brain interaction disorders: A comparative study using the lactulose breath test. World J Gastrointest Pathophysiol 2025; 16(4): 110421 |
| URL |
https://www.wjgnet.com/2150-5330/full/v16/i4/110421.htm |
| DOI |
https://dx.doi.org/10.4291/wjgp.v16.i4.110421 |
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