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8/18/2025 10:04:52 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 110481
Country United Kingdom
Received
2025-06-10 01:27
Peer-Review Started
2025-06-10 01:27
To Make the First Decision
Return for Revision
2025-06-17 10:46
Revised
2025-06-30 03:49
Second Decision
2025-07-25 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-25 05:43
Articles in Press
2025-07-25 05:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-08 02:08
Publish the Manuscript Online
2025-08-18 10:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Skeletal muscle alterations in metabolic dysfunction-associated steatotic liver disease: A critical review of diagnostic, mechanistic, and therapeutic intersections
Manuscript Source Unsolicited Manuscript
All Author List Vaynika Gupta and Ashwin Krishnamoorthy
ORCID
Author(s) ORCID Number
Vaynika Gupta http://orcid.org/0009-0002-5822-2936
Ashwin Krishnamoorthy http://orcid.org/0000-0003-2480-8664
Funding Agency and Grant Number
Corresponding Author Vaynika Gupta, College of Medicine and Health, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom. vxg381@student.bham.ac.uk
Key Words Metabolic dysfunction-associated steatotic liver disease; Skeletal muscle alterations; Sarcopenia; Myosteatosis; Muscle metabolism; Physical activity; Glucagon-like peptide-1 receptor agonistsMetabolic dysfunction-associated steatotic liver disease; Skeletal muscle alterations; Sarcopenia; Myosteatosis; Muscle metabolism; Physical activity; Glucagon-like peptide-1 receptor agonists
Core Tip Skeletal muscle alterations, such as sarcopenia, myosteatosis, and metabolic dysregulation, are increasingly common in pathogenesis and progression of metabolic dysfunction-associated steatotic liver disease. Underlying mechanisms, including insulin resistance, inflammation, and myokine imbalance, along with emerging biomarkers offer opportunities to study lifestyle and pharmacological interventions such as glucagon-like peptide-1 agonists. Further development must build on gaps in current literature, standardize diagnostic criteria and evaluate translational data for clinical applicability.
Publish Date 2025-08-18 10:04
Citation <p>Gupta V, Krishnamoorthy A. Skeletal muscle alterations in metabolic dysfunction-associated steatotic liver disease: A critical review of diagnostic, mechanistic, and therapeutic intersections. <i>World J Gastroenterol</i> 2025; 31(31): 110481</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i31/110481.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i31.110481
Full Article (PDF) WJG-31-110481-with-cover.pdf
Manuscript File 110481_Auto_Edited_074713.docx
Answering Reviewers 110481-answering-reviewers.pdf
Audio Core Tip 110481-audio.mp3
Conflict-of-Interest Disclosure Form 110481-conflict-of-interest-statement.pdf
Copyright License Agreement 110481-copyright-assignment.pdf
Peer-review Report 110481-peer-reviews.pdf
Scientific Misconduct Check 110481-scientific-misconduct-check.png
Scientific Editor Work List 110481-scientific-editor-work-list.pdf
CrossCheck Report 110481-crosscheck-report.pdf